• Organization: National Aeronautics and Space Administration
• Updated: 2026-02-10

Collaborative Research: A RAPID response to Hurricane Harvey's impacts on coastal carbon cycle, metabolic balance and ocean acidification.

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• Organization: U.S. Environmental Protection Agency
• Updated: 2023-11-18

The supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/toxics11120951/s1. Text S1: Chemicals; Text S2: Thyroid Hormone Chemicals and Analysis; Text S3: In Vivo...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Changes in gene expression profiles implicated in oxidative stress and in ECM remodeling in mouse skin were examined after space flight. The metabolic effects of space flight in skin tissues were...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Rheumatoid arthritis (RA) patients experience a markedly increased frequency of cardiovascular disease. We evaluated cardiovascular risk profiles in 79 RA patients and in 39 age-matched and...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and metabolic differences...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and metabolic differences...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2020-01-21

A manuscript describing the independent roles of beta adrenergic and glucocorticoid receptors in mediating ozone-induced pulmonary and systemic effects. This dataset is associated with the...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2022-06-23

This ScienceHub file shows the physiological data associated with the manuscript Adrenal Stress Hormone Regulation of Hepatic Homeostatic Function After an Acute Ozone Exposure in Wistar-Kyoto...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

p53 performs a plethora of activities, which are directed towards the maintenance of the genomic integrity and constitute its universal role as a tumor suppressor. 1000 to 10000 latent...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

A novel nuclear receptor, termed the steroid and xenobiotic receptor (SXR), a broad-specificity sensing receptor that is a novel branch of the nuclear receptor superfamily, has been discovered....

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• Organization: U.S. Environmental Protection Agency
• Updated: 2016-09-01

This dataset contains model code and supporting analysis files necessary to evaluate the impact of variability in human hepatic scaling factors. Variation in scaling factor values impacts...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut biomedical profiles. These...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2019-12-12

The eastern oyster (Crassostrea virginica) supports a large aquaculture industry and is a keystone species along the Atlantic seaboard. Native oysters are routinely exposed to a complex mixture of...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2020-11-30

In this study, using male Wistar and Wistar-derived Goto-Kakizaki (GK) rats, which exhibit a non-obese type-2 diabetes phenotype, we investigated whether two key metabolic stressors, type-2...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-10-16

The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and metabolic differences...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

The first global genomic proteomic and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the International Space Station (ISS) is...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

The first global genomic, proteomic, and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the International Space Station (ISS) is...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila aboard the International...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila aboard the International...

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