Found 363 datasets matching "mice".
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Cardiac and ventilatory physiological data for mice exposed to acrolein. This dataset is associated with the following publication: Kurhanewicz, N., A. Ledbetter, A. Farraj, and M. Hazari. TRPA1...
Search relevance: 118.46 | Views last month: 0 -
Background Excessive loss of bile acids in stool has been reported in patients with cystic fibrosis. Some data suggest that a defect in mucosal bile acid transport may be the mechanism...
Search relevance: 114.80 | Views last month: 0 -
Anti-tumor-necrosis-factor-α (TNF-α) monoclonal antibody was used to treat Tg197 transgenic mice, which constitutively produce human TNF-α (hTNF-α) and develop a progressive polyarthritic disease....
Search relevance: 114.74 | Views last month: 0 -
Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice....
Search relevance: 107.10 | Views last month: 1 -
In 2013, a large blinded, paired placebo-controlled field trial for the prairie dog oral sylvatic plague vaccine started in the Western US. On 17 paired plots, vaccine and placebo plots, small...
Search relevance: 105.07 | Views last month: 1 -
Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months of age, most female transgenics...
Search relevance: 102.94 | Views last month: 0 -
Background CMV infections have been linked to vasculopathies like atherosclerosis and Scleroderma. CMV infects vascular endothelium with intermittent shedding of the virus and the...
Search relevance: 102.29 | Views last month: 0 -
Background Cadmium poisoning in the environment has assumed an alarming problem in recent years. Effective antimutagenic agents which can reverse or combat cadmium induced genotoxicity...
Search relevance: 99.08 | Views last month: 0 -
The dataset consists of 2 revised files. The excel file shows all of the individual data used in calculation of the tables and figures. Each table and figure has data stored on a separate tab of...
Search relevance: 97.25 | Views last month: 0 -
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked...
Search relevance: 96.77 | Views last month: 0 -
Background Non-invasive autofluorescent reporters have revolutionized lineage labeling in an array of different organisms. In recent years green fluorescent protein (GFP) from the...
Search relevance: 92.01 | Views last month: 0 -
This work is part of an experimental trial to develop and assess novel recombinant raccoonpox virus (RCN) rabies vaccines in the mouse model, for potential use in bats. Briefly, our research group...
Search relevance: 90.62 | Views last month: 0 -
This U.S. Geological Survey (USGS) data release represents tabular data that were used to develop the Biological Objectives for the Gulf Coast Project’s Beach Mice Bayesian network model. The USGS...
Search relevance: 88.96 | Views last month: 2 -
Background Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in multidisciplinary genetic...
Search relevance: 87.98 | Views last month: 7 -
Background The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO). Inhibition of COMT, as opposed to MAO,...
Search relevance: 87.52 | Views last month: 0 -
Germline mutations in the tumor suppressorPTENpredispose human beings to breast cancer, and genetic and epigenetic alterations ofPTENare also detected in sporadic human breast cancer....
Search relevance: 86.90 | Views last month: 0 -
Background The rapid increase in the development of mouse models is resulting in a growing demand for non-invasive physiological monitoring of large quantities of mice. Accordingly, we...
Search relevance: 86.46 | Views last month: 1 -
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to determine the levels of...
Search relevance: 85.92 | Views last month: 0 -
Background The importance of nitric oxide (NO) in hypoxic pulmonary hypertension has been demonstrated using nitric oxide synthase (NOS) knockout mice. In that model NO from endothelial...
Search relevance: 85.04 | Views last month: 0 -
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the arteries, veins, and...
Search relevance: 84.82 | Views last month: 0
