Found 15 datasets matching "mitochondrial-stress".
-
Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut biomedical profiles. These...
Search relevance: 151.51 | Views last month: 0 -
Background The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. Mitochondria are one of the major...
Search relevance: 115.26 | Views last month: 0 -
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics analysis based on mass...
Search relevance: 92.55 | Views last month: 0 -
Figure 1. Comparison of cell viability in response to exposure of cells to oleic acid (in ethanol), a hydroxy-metabolite, or methylated oleic acid as percent of the vehicle control response....
Search relevance: 57.19 | Views last month: 1 -
['Physical inactivity is a risk factor for insulin resistance. We examined the effect of nine days of bed rest on basal and insulin stimulated expression of genes potentially involved in insulin...
Search relevance: 53.94 | Views last month: 0 -
Background Dehydrins are known as Group II late embryogenesis abundant proteins. Their high hydrophilicity and thermostability suggest that they may be structure stabilizers with...
Search relevance: 53.27 | Views last month: 0 -
Background Oxidative stress plays a major role in the biochemical and pathological changes associated with myocardial ischemic-reperfusion injury (IRI). The need to identify agents with...
Search relevance: 53.24 | Views last month: 0 -
Background Living cells constantly sense and adapt to redox shifts by the induction of genes whose products act to maintain the cellular redox environment. In the eukaryote Saccharomyces...
Search relevance: 48.55 | Views last month: 0 -
Prolonged residence of mice in spaceflight is a scientifically robust and ethically ratified model of muscle atrophy caused by continued unloading. Under the Rodent Research Program of NASA, we...
Search relevance: 44.40 | Views last month: 0 -
The response of plants to the spaceflight environment and microgravity is still not well understood although there has been an increased emphasis on this topic. Even less is known about plants ...
Search relevance: 44.00 | Views last month: 0 -
Background Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy (DN). Antioxidant...
Search relevance: 37.30 | Views last month: 0 -
Background It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively...
Search relevance: 36.71 | Views last month: 0 -
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to characterize the effects of...
Search relevance: 31.41 | Views last month: 0 -
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to characterize the effects of...
Search relevance: 30.51 | Views last month: 3 -
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to characterize the effects of...
Search relevance: 30.51 | Views last month: 0
