Found 82 datasets matching "peptide".
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Background Major histocompatibility complex (MHC) molecules present peptides to T lymphocytes. It is of critical biological and medical importance to elucidate how different MHC alleles...
Search relevance: 137.92 | Views last month: 1 -
Background Quantitative information on the types of inter-atomic interactions at the MHC-peptide interface will provide insights to backbone/sidechain atom preference during binding....
Search relevance: 132.01 | Views last month: 0 -
Background Increasing evidence suggests that the effect of HLA-E on Natural Killer (NK) cell activity can be affected by the nature of the peptides bound to this non-classical, MHC class...
Search relevance: 130.84 | Views last month: 1 -
Background Cathepsin B is thought to play a central role in intrapancreatic trypsinogen activation and the onset of pancreatitis. A recent investigation of the cathepsin B mediated...
Search relevance: 126.40 | Views last month: 0 -
Background: Cerebral vasospasm is a poor resulting outcome of a ruptured cerebral aneurysm; to clarify the mechanism of vasospasm it is important to improve this outcome. C-type...
Search relevance: 114.02 | Views last month: 1 -
We have recently found that matrix metalloproteinases (MMPs) are targets for T-cell and B-cell reactivity in experimental arthritis. In the present article, we investigate whether modulation of...
Search relevance: 94.51 | Views last month: 0 -
A novel peptide sequence having the general formula AB wherein each of A and B represent a chain of amino acid residues and wherein said A chain is capable of binding with a mojor...
Search relevance: 92.39 | Views last month: 0 -
A process for the synthesis, in liquid phase and by fragments, of hGRF 1-44 and hGRF 1-40. This process consists in coupling, one after the other and in the order of the sequence of the GRF, (1)...
Search relevance: 92.20 | Views last month: 0 -
NIST peptide libraries are comprehensive, annotated mass spectral reference collections from various organisms and proteins useful for the rapid matching and identification of acquired MS/MS...
Search relevance: 91.03 | Views last month: 1 -
Most techniques that identify antigen-specific T cells are dependent on the response of these cells to the relevant antigen in culture. Soluble multimers of MHC molecules, when occupied with the...
Search relevance: 89.10 | Views last month: 0 -
Background In addition to endogenous opioids, a number of peptide sequences, derived from endogenous (hemorphins, alphaS1-casomorphin), and exogenous proteins (casomorphins, exorphins)...
Search relevance: 81.77 | Views last month: 1 -
Background Bone remodelling is dependent on the balance between bone resorbing osteoclasts and bone forming osteoblasts. We have shown previously that osteoclasts contain gap-junctional...
Search relevance: 79.98 | Views last month: 0 -
Human myelin basic protein (h-MBP) has a molecular weight of 18.5 KD and contains 170 amino acid residues. Synthetic peptides ranging in length from about 8 to 25 residues and covering the entire...
Search relevance: 77.76 | Views last month: 0 -
Background Transcriptional transactivation is a process with remarkable tolerance for sequence diversity and structural geometry. In studies of the features that constitute...
Search relevance: 75.98 | Views last month: 0 -
Aim: To study the effects of infusion of atrial natriuretic peptide (ANP) versus the inhalation of nitric oxide (NO) in patients with an early acute respiratory distress syndrome...
Search relevance: 72.04 | Views last month: 0 -
The spreadsheet file reported herein provides centroid data, descriptive of deuterium uptake, for the Fab Fragment of NISTmAb (PDB: 5K8A) reference material, as measured by the bottom-up...
Search relevance: 63.38 | Views last month: 0 -
The large surface area, good vascularization, immense capacity for solute exchange and ultra-thinness of the alveolar epithelium are unique features of the lung that can facilitate systemic...
Search relevance: 61.19 | Views last month: 0 -
The present invention relates to compositions and methods for expressing mini-dystrophin peptides. In particular, the present invention provides compositions comprising nucleic acid sequences that...
Search relevance: 54.02 | Views last month: 0 -
The present invention is directed to antixoidant peptides produced by the proteolytic digestion of soy protein isolate. These peptides may be purified and used in either pharmaceutical or dietary...
Search relevance: 53.37 | Views last month: 0
