Found 48 datasets matching "phosphorylation".
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Background Two-component systems consisting of histidine kinases and their corresponding receivers are widespread in bacterial signal transduction. In the past few years, genes coding...
Search relevance: 144.73 | Views last month: 0 -
Background In S. cerevisiae, the mitotic exit network (MEN) proteins, including the Polo-like protein kinase Cdc5 and the protein phosphatase Cdc14, are required for exit from mitosis....
Search relevance: 131.75 | Views last month: 0 -
Background Structural requirements for the β1 integrin functions in cell adhesion, spreading and signaling have been well documented mainly for fibroblasts. In this study, we examined...
Search relevance: 115.24 | Views last month: 0 -
Background The 85-kDa cytosolic phospholipase A2 (cPLA2) mediates arachidonic acid (AA) release in MDCK cells. Although calcium and mitogen-activated protein kinases regulate cPLA2, the...
Search relevance: 80.64 | Views last month: 0 -
Background The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53...
Search relevance: 74.78 | Views last month: 0 -
Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Search relevance: 74.38 | Views last month: 0 -
Background STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6 signaling and...
Search relevance: 73.84 | Views last month: 0 -
The adaptor protein p130Cas(Cas) has been shown to be involved in different cellular processes including cell adhesion, migration and transformation. This protein has a substrate domain with up to...
Search relevance: 73.64 | Views last month: 0 -
Background The mos proto-oncogene encodes a cytoplasmic serine/threonine-specific protein kinase with crucial function during meiotic cell division in vertebrates. Based on oncogenic...
Search relevance: 72.90 | Views last month: 0 -
Background In this study, we investigated the mechanism(s) by which delta opioids induce their potent activation of extracellular signal-regulated protein kinases (ERKs) in different...
Search relevance: 70.54 | Views last month: 0 -
Background Bone morphogenetic proteins (BMPs) and transforming growth factor-βs (TGF-βs) are important regulators of bone repair and regeneration. BMP-2 and TGF-β1 have been shown to...
Search relevance: 70.45 | Views last month: 0 -
Background The mechanisms by which alpha-2 adrenergic receptors are down-regulated following chronic exposure to agonist are not well understood. Interestingly, the human alpha-2C...
Search relevance: 68.82 | Views last month: 0 -
Background Vaccinia virus gene B1R encodes a serine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R,...
Search relevance: 68.02 | Views last month: 0 -
Background Cortical myosin-II filaments in Dictyostelium discoideum display enrichment in the posterior of the cell during cell migration and in the cleavage furrow during cytokinesis....
Search relevance: 53.97 | Views last month: 0 -
The dataset include the following figures and tables: 1)Changes in protein expression of the 14 pathway regulators induced by Ni (II). 2)Hierarchical clustering of 12 differentially expressed or...
Search relevance: 53.78 | Views last month: 0 -
Background Dictyostelium cells exhibit an unusual stress response as they protect themselves against hyperosmotic stress. Cytoskeletal proteins are recruited from the cytosolic pool to...
Search relevance: 46.64 | Views last month: 0 -
Conventional molecular dynamics (MD) simulations using the GPU-enabled CUDA version of the pmemd executable (pmemd.cuda) in AMBER were applied to explore the structure and dymanics of MAPK, ERK2....
Search relevance: 45.29 | Views last month: 0 -
Background Cyclic nucleotides can relax vascular smooth muscle by mechanisms distal to myosin regulatory light chain (MRLC) phosphorylation. This mechanism, termed relaxation without...
Search relevance: 41.74 | Views last month: 0 -
Background During cytokinesis, the cell's equator contracts against the cell's global stiffness. Identifying the biochemical basis for these mechanical parameters is essential for...
Search relevance: 41.27 | Views last month: 2 -
Background The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. Mitochondria are one of the major...
Search relevance: 40.32 | Views last month: 0
