Found 42 datasets matching "protein-interaction".
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Background The cyclic AMP specific phosphodiesterase, PDE4D5 interacts with the β-propeller protein RACK1 to form a signaling scaffold complex in cells. Two-hybrid analysis of truncation...
Search relevance: 110.12 | Views last month: 0 -
Background The CD98 (4F2, FRP-1) is a widely expressed cell surface protein heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain. Originally described as...
Search relevance: 87.88 | Views last month: 0 -
Background It has recently been shown that the detection of gene fusion events across genomes can be used for predicting functional associations of proteins, including physical...
Search relevance: 84.47 | Views last month: 0 -
Background The malarial parasite, Plasmodium falciparum (Pf), is responsible for nearly 2 million deaths worldwide. However, the mechanisms of cellular signaling in the parasite remain...
Search relevance: 65.10 | Views last month: 0 -
The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein...
Search relevance: 61.68 | Views last month: 45 -
Background The mechanism of aluminum-induced neurotoxicity is not clear. The involvement of glutamate in the aluminium-induced neurocomplications has been suggested. Brain glutamate...
Search relevance: 61.22 | Views last month: 0 -
BioGRID is an online interaction repository with data on raw protein and genetic interactions from major model organism species. All interaction data are freely provided through our search index...
Search relevance: 60.43 | Views last month: 0 -
Background Protein-protein interactions have decisive roles in almost all aspects of the structural and functional organization of cells. But in spite of the increasing amount of...
Search relevance: 60.18 | Views last month: 0 -
Background The C-terminal four amino acids (GEEV) of human α1A-adrenergic receptors (ARs) have been reported to interact with the PDZ domain of neuronal nitric oxide synthase (nNOS) in a...
Search relevance: 58.74 | Views last month: 0 -
Background DAZAP1 (DAZ Associated Protein 1) was originally identified by a yeast two-hybrid system through its interaction with a putative male infertility factor, DAZ (Deleted in...
Search relevance: 57.93 | Views last month: 0 -
The invention relates to the identification of a new protein that binds to the cytoplasmic domain of syndecan. This new protein, denominated as "syntenin", contains 298 amino acids and is...
Search relevance: 56.71 | Views last month: 0 -
Background Epstein-Barr virus (EBV) infects resting B-lymphocytes and transforms them into immortal proliferating lymphoblastoid cell lines (LCLs) in vitro. The transformed immunoblasts...
Search relevance: 55.43 | Views last month: 0 -
Background Virulence genes on Salmonella pathogenicity island 1 (SPI1) are coordinately regulated by HilA, a member of the OmpR/ToxR family of transcription factors. Although a great...
Search relevance: 53.25 | Views last month: 0 -
NCBI Virus is an integrative, value-added resource designed to support retrieval, display and analysis of a curated collection of virus sequences and large sequence datasets. Its goal is to...
Search relevance: 51.83 | Views last month: 31 -
Information about retroviruses and specialized tools for the analysis of retroviral proteins and genomes. The tools on this page aid in the identification, study and analysis of retroviral genomes...
Search relevance: 49.64 | Views last month: 2 -
Background Secretion of anti-host proteins by Yersinia pestis via a type III mechanism is not constitutive. The process is tightly regulated and secretion occurs only after an...
Search relevance: 48.86 | Views last month: 0 -
Background Detection of changes in a protein's evolutionary rate may reveal cases of change in that protein's function. We developed and implemented a simple relative rates test in an...
Search relevance: 48.05 | Views last month: 0 -
Background Patients with Opitz GBBB syndrome present with a variable array of developmental defects including craniofacial, cardiac, and genital anomalies. Mutations in the X-linked MID1...
Search relevance: 47.94 | Views last month: 0 -
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-expressing yeast cells. In this paper...
Search relevance: 47.50 | Views last month: 0 -
Background Studies examining herpesvirus-herpesvirus (cytomegalovirus (CMV)-Epstein-Barr virus (EBV)) interactions are limited, and many of the studies have been clinical observations...
Search relevance: 47.45 | Views last month: 0