Catalog - Data.gov

Found 5 datasets matching "quantitative AOP".

#1 Federal
Conolly, R.B., Ankley, G.T., Cheng, WY., Mayo, M.L., Miller, D.H., Perkins, E.J., Villeneuve, D.L., and Watanable, K.H. (2017). Quantitative adverse outcome pathways and their application ot predictive toxicology. Environ. Sci. Technol. 51, 4661–4672
- Organization: U.S. Environmental Protection Agency
- Updated: 2017-03-29
A publised mansucript describing a quantitative adverse outcome pathway (qAOP) and its relevance to risk assessment. This dataset is not publicly accessible because: This work describes...

Search relevance: 58.72 | Views last month: 0
#2 Federal
Advancing the Adverse Outcome Pathway Concept – An International ‘Horizon Scanning’ Approach
- Organization: U.S. Environmental Protection Agency
- Updated: 2016-08-30
Our ability to conduct whole organism toxicity tests to understand chemical safety has been outpaced by our ability to synthesize new chemicals for a wide variety of commercial applications. ...

Search relevance: 58.29 | Views last month: 0
#3 Federal
IN VITRO AND IN VIVO ANDROGEN RECEPTOR DATA SET FROM TOX SCI PAPER GRAY ET AL 2020
- Organization: U.S. Environmental Protection Agency
- Updated: 2020-10-22
Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house...
- pdf
- pdf
- xml
- xml
Search relevance: 49.26 | Views last month: 0
#4 Federal
Case study in 21st century ecotoxicology: using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish
- Organization: U.S. Environmental Protection Agency
- Updated: 2020-10-06
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
- xml
Search relevance: 44.48 | Views last month: 2
#5 Federal
Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene Expression in the Ovary of Female Fathead Minnows (Pimephales promelas)
- Organization: U.S. Environmental Protection Agency
- Updated: 2017-02-23
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
- none
- xml
- xml
- xml
- none
- xml
- +1 more
Search relevance: 41.21 | Views last month: 1

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Conolly, R.B., Ankley, G.T., Cheng, WY., Mayo, M.L., Miller, D.H., Perkins, E.J., Villeneuve, D.L., and Watanable, K.H. (2017). Quantitative adverse outcome pathways and their application ot predictive toxicology. Environ. Sci. Technol. 51, 4661–4672

Advancing the Adverse Outcome Pathway Concept – An International ‘Horizon Scanning’ Approach

IN VITRO AND IN VIVO ANDROGEN RECEPTOR DATA SET FROM TOX SCI PAPER GRAY ET AL 2020

Case study in 21st century ecotoxicology: using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish

Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene Expression in the Ovary of Female Fathead Minnows (Pimephales promelas)