Found 28 datasets matching "reporter gene".
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['Microgravity is one of the most important features in spaceflight. Previous evidence has shown that significant changes to the musculoskeletal and immune systems occurred under microgravity. The...
Search relevance: 82.71 | Views last month: 0 -
Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The regulatory mechanisms...
Search relevance: 79.29 | Views last month: 1 -
Background Several Cre reporter strains of mice have been described, in which a lacZ gene is turned on in cells expressing Cre recombinase, as well as their daughter cells, following...
Search relevance: 63.96 | Views last month: 0 -
Background The hepatic stellate cell is the primary cell type responsible for the excessive formation and deposition of connective tissue elements during the development of hepatic...
Search relevance: 63.28 | Views last month: 2 -
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches were used; GFP reporter genes...
Search relevance: 60.57 | Views last month: 0 -
The toxicity of sediments in Biscayne Bay and many adjoining tributaries was determined as part of a bioeffects assessments program managed by NOAA's National Status and Trends Program. Biscayne...
Search relevance: 60.45 | Views last month: 0 -
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches were used; GFP reporter genes...
Search relevance: 60.18 | Views last month: 0 -
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches were used; GFP reporter genes...
Search relevance: 60.18 | Views last month: 0 -
Background The acetamidase of Mycobacterium smegmatis is a highly inducible enzyme. Expression of this enzyme is increased 100-fold when the substrate acetamide is present. The...
Search relevance: 58.05 | Views last month: 0 -
The toxicity of sediments in Sabine Lake, Texas, and adjoining Intracoastal Waterway canals was determined as part of bioeffects assessment studies managed by NOAA's National Status and Trends...
Search relevance: 56.76 | Views last month: 1 -
Background Retinoids are very potent inducers of cellular differentiation and apoptosis, and are efficient anti-tumoral agents. Synthetic retinoids are designed to restrict their...
Search relevance: 53.17 | Views last month: 0 -
Background Non-invasive autofluorescent reporters have revolutionized lineage labeling in an array of different organisms. In recent years green fluorescent protein (GFP) from the...
Search relevance: 52.22 | Views last month: 0 -
Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints. Table S2. Agreement with OECD reference AR agonists. Table S3. Agreement with OECD reference ER...
Search relevance: 50.76 | Views last month: 0 -
Background The serum response element (SRE) in the c-fos promoter is a convergence point for several signaling pathways that regulate induction of the c-fos gene. Many transcription...
Search relevance: 50.33 | Views last month: 0 -
The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist activity. Active compounds were...
Search relevance: 49.50 | Views last month: 2 -
Background Polyamine synthesis produces methylthioadenosine, which has to be disposed of. The cell recycles it into methionine through methylthioribose (MTR). Very little was known about...
Search relevance: 48.41 | Views last month: 0 -
Interleukin-1 receptor antagonist (IL-1Ra) is a natural IL-1 inhibitor possessing anti-inflammatory properties. IL-1Ra is produced as different isoforms, one secreted (sIL-1Ra) and three...
Search relevance: 47.69 | Views last month: 0 -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 46.25 | Views last month: 0 -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 46.25 | Views last month: 0 -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 45.70 | Views last month: 1
