Found 50 datasets matching "sepsis".
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Great advances have been made in describing the intracellular pathways and genes that are activated by bacterial products. New definitions and therapies for sepsis will be based on such cellular...
Search relevance: 157.87 | Views last month: 2 -
The datasets include severe sepsis information on 1) the number of severe sepsis cases, percent of hospital-acquired and non-hospital-acquired severe sepsis cases, and the percent of in-hospital...
Search relevance: 157.56 | Views last month: 0 -
Part of Stephan Jakob's exhaustive review paper in the present issue of Critical Care deals with the notion that intestinal cellular energetics are deranged in sepsis, in terms not only of...
Search relevance: 153.67 | Views last month: 0 -
Introduction The aim of the study was to assess the prognostic importance of basal cortisol concentrations and cortisol response to corticotropin, and to determine the effects of...
Search relevance: 142.67 | Views last month: 0 -
The present review discusses the hemodynamic effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of hypertonic saline, calling...
Search relevance: 140.42 | Views last month: 1 -
The dataset contains in-hospital postoperative sepsis cases, elective surgical discharges, risk-adjusted sepsis rates, and performance ratings for California hospitals. This dataset does not...
Search relevance: 139.10 | Views last month: 0 -
Introduction In this prospective, randomized controlled study, we aimed to evaluate the effect of IgM-enriched immunoglobulin treatment on progression of organ failure and septic shock...
Search relevance: 134.79 | Views last month: 0 -
Corticosteroid treatment of severe sepsis has been one of the most controversial clinical issues in critical care. In fact, few agents can claim to have been evaluated in scores of studies...
Search relevance: 134.01 | Views last month: 1 -
Introduction Treatment of patients with severe sepsis with agents antagonising the effects of C5a has been proposed based on beneficial effects in animal experiments and in vitro studies...
Search relevance: 130.33 | Views last month: 0 -
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in acute lung injury...
Search relevance: 129.93 | Views last month: 0 -
Background: Increased serum levels of procalcitonin (ProCT) and its component peptides have been reported in humans with sepsis. Using a hamster model of bacterial peritonitis,...
Search relevance: 129.58 | Views last month: 0 -
Introduction Treatment of sepsis is aimed at increasing both the duration and quality of survival. A long-term focus on quality of life (QoL) in clinical trial evaluations of sepsis care...
Search relevance: 124.27 | Views last month: 1 -
Associations between cytokines assessed in EBC and the outcomes of Death, Pneumonia, and Sepsis. An odds ratio greater than 1 is indicative of a positive association between the cytokine and the...
Search relevance: 114.92 | Views last month: 0 -
Despite decades of resuscitating patients with intravenous fluids in intensive care units, it is somewhat surprising that very little consensus exists regarding the type of fluid physicians should...
Search relevance: 111.69 | Views last month: 0 -
Background: We studied the incidence of withholding or withdrawing therapeutic measures in intensive care unit (ICU) patients, as well as the possible implications of sepsis-related...
Search relevance: 100.50 | Views last month: 2 -
Objectives: The relation of procalcitonin (PCT) plasma concentrations compared with C-reactive protein (CRP) was analyzed in patients with different severity of multiple organ...
Search relevance: 93.91 | Views last month: 1 -
Background Lipopolysaccharide (endotoxin) from the cell wall of Gram-negative bacteria is a potent trigger for the release of host-derived inflammatory mediators. The relationship...
Search relevance: 75.52 | Views last month: 1 -
Introduction The administration of antithrombin III (ATIII) is useful in patients with congenital deficiency, but evidence for the other therapeutic indications of this drug is still...
Search relevance: 70.71 | Views last month: 0 -
The use of corticosteroids in septic shock remains controversial. It has been demonstrated that high doses of steroids (30 mg/kg methylprednisolone) for short periods of time are not beneficial....
Search relevance: 68.64 | Views last month: 1 -
Introduction: Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions among demographics, physiologic...
Search relevance: 67.40 | Views last month: 1