Found 28 datasets matching "t-cell-response".
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The pathogenesis of systemic vasculitis is complex and is likely to involve many mechanisms. There is a growing body of evidence that T cells may contribute to the pathogenesis of anti-neutrophil...
Search relevance: 120.56 | Views last month: 1 -
The immunodominant T-cell epitope that is involved in collagen-induced arthritis (CIA) is the glycosylated type II collagen (CII) peptide 256-270. In CII transgenic mice, which express the...
Search relevance: 115.00 | Views last month: 0 -
IFN-γ was measured in supernatants after in vitro stimulation of peripheral blood mononuclear cells with collagen type II (CII), purified protein derivative or influenza virus. IFN-γ production in...
Search relevance: 106.28 | Views last month: 0 -
In rheumatoid arthritis, T cells and B cells participate in the immune responses evolving in the synovial lesions. Interaction between T cells and B cells is probably antigen specific because...
Search relevance: 74.83 | Views last month: 0 -
Background Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would be important to...
Search relevance: 72.35 | Views last month: 0 -
T lymphocytes play a key role in the immune response to both foreign and self peptide antigens, which they recognize in combination with MHC molecules. In the past it has been difficult to analyse...
Search relevance: 66.59 | Views last month: 0 -
Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Search relevance: 64.36 | Views last month: 0 -
This data set contains supporting information for the article: Analysis of Microcystins in Alum Water Treatment Sludges: Holding Times, Temperatures, Linearity of Response, and Sensitivity to...
Search relevance: 64.34 | Views last month: 0 -
Background T cells from HIV+ and aged individuals show parallels in terms of suppressed proliferative activity and interleukin-2 (I1-2) production and an increased number of CD8+ CD28- T...
Search relevance: 63.62 | Views last month: 1 -
Background It has been proposed that outer surface protein A (OspA) of Borrelia burgdorferi sensu stricto contains a T helper 1 (Th1) cell epitope that could play a role in an autoimmune...
Search relevance: 63.03 | Views last month: 0 -
The production of superantigenic exotoxins by Gram positive bacteria underlies the pathology of toxic shock syndrome. Future treatment strategies for superantigen-mediated diseases are likely to...
Search relevance: 59.01 | Views last month: 0 -
A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent antibodies to glucose-6-phosphate...
Search relevance: 57.16 | Views last month: 0 -
Dose response viability data of rat and human intestinal cells exposed to copper oxide nanoparticles (CuO, Cu2O), CuSO4 and CuCl (rat cells only). Assays examining a potential mechanism of...
Search relevance: 55.37 | Views last month: 0 -
Background Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce...
Search relevance: 54.69 | Views last month: 0 -
Background Treatment of mouse F9 embryonal carcinoma cells with all-trans retinoic acid (T-RA) induces differentiation into primitive endodermal type cells. Differentiation requires the...
Search relevance: 53.25 | Views last month: 0 -
Background Invasion and metastasis is a complex process governed by the interaction of genetically altered tumor cells and the immunological and inflammatory host reponse. Specific...
Search relevance: 51.39 | Views last month: 0 -
Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging to the host that produces...
Search relevance: 51.11 | Views last month: 0 -
N/A. This dataset is associated with the following publication: Hughes, M., M. Devito, G. Patlewicz, R. Thomas, L. Adams, J. Ambroso, X. Yang, B. Upadhyay, S. Burleson, and E. Kenyon....
Search relevance: 49.85 | Views last month: 0 -
The Vegetation/Ecosystem Modeling and Analysis Project (VEMAP) is an ongoing multiinstitutional, international effort addressing the response of biogeography and biogeochemistry to environmental...
Search relevance: 48.67 | Views last month: 0