Found 16 datasets matching "thymus".
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The thymus undergoes atrophy during spaceflight. In this study we analyzed gene expression of the thymus of mice on board International space station to elucidate molecular aspects of the thymic...
Search relevance: 121.15 | Views last month: 0 -
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene expression of...
Search relevance: 104.89 | Views last month: 0 -
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene expression of...
Search relevance: 101.10 | Views last month: 0 -
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the arteries, veins, and...
Search relevance: 86.77 | Views last month: 0 -
The Spacelab Life Sciences (SLS) program was a series of payloads that used the facilities of an entire Spacelab module to conduct a variety of life science investigations. The general objective...
Search relevance: 85.79 | Views last month: 0 -
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration spaceflight, particularly visual...
Search relevance: 79.32 | Views last month: 0 -
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to mitigate muscle wasting. The...
Search relevance: 74.68 | Views last month: 1 -
Data objects used for analysis in "A single-cell immune atlas of primary and secondary lymphoid organs in pigs" by Wiarda et al. Data objects include .cloupe files for interactive query in Loupe...
Search relevance: 58.88 | Views last month: 1 -
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus...
Search relevance: 45.31 | Views last month: 2 -
Most patients with rheumatoid arthritis (RA) express HLA-DR4, HLA-DR1 or HLA-DR10. These alleles share a common amino acid motif in their third hypervariable regions: the shared epitope. In...
Search relevance: 38.52 | Views last month: 0 -
This work is part of a study of the immunological effects of exposure to alternative flame retardants in avian species. For the pathology portion of the study, hatchling American kestrels (Falco...
Search relevance: 37.20 | Views last month: 0 -
Ozone exposure induces neuroendocrine stress response, which causes lymphopenia. We hypothesized that ozone-induced increases in stress hormones will temporally follow changes in circulating...
Search relevance: 30.02 | Views last month: 0 -
Background The immune system is particularly sensitive to stress. Although acute stress generally has positive effects, chronic stress typically provokes immunosuppression. The...
Search relevance: 28.29 | Views last month: 0 -
Background Allergic Contact Dermatitis (ACD) is regarded as a T-cell-mediated delayed-type hypersensitivity reaction. We studied the kinetics of the expression of CS-1 fibronectin,...
Search relevance: 27.69 | Views last month: 0 -
Bats of the genus Lasiurus occur throughout the Americas and have diversified into at least 20 species among three subgenera. The hoary bat (Lasiurus cinereus, or synonymously, Aeorestes cinereus)...
Search relevance: 27.28 | Views last month: 0 -
Background The function of the thymic microenvironment is to promote thymocyte maturation, in part via regulation of thymocyte proliferation and cell death. Defects in fetal thymic...
Search relevance: 27.04 | Views last month: 0
