Found 156 datasets matching "tumor".
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Background It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal...
Search relevance: 122.23 | Views last month: 0 -
Background The purpose of this study was to use insurance claims and tumor registry data to examine determinants of breast conserving surgery (BCS) in women with early stage breast...
Search relevance: 121.23 | Views last month: 3 -
Background The EST database provides a rich resource for gene discovery and in silico expression analysis. We report a novel computational approach to identify co-expressed genes using...
Search relevance: 120.16 | Views last month: 0 -
Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous...
Search relevance: 119.64 | Views last month: 0 -
Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional study of newly...
Search relevance: 116.73 | Views last month: 1 -
Aims and background The Ki-67 is a nuclear antigen detected by the monoclonal antibody MIB-1 and its Labeling Index (LI) is considered a marker of normal and abnormal cell proliferation....
Search relevance: 109.39 | Views last month: 0 -
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in addition to...
Search relevance: 99.44 | Views last month: 0 -
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in addition to...
Search relevance: 98.97 | Views last month: 0 -
Age plays a major role in tumor incidence and is an important consideration when modeling the carcinogenesis process or estimating cancer risks. Epidemiological data show that from adolescence...
Search relevance: 97.66 | Views last month: 0 -
Combined cancer registry data from all VHA facilities. Includes North American Association of Central Cancer Registries, Inc. (NAACCR).
Search relevance: 96.23 | Views last month: 4 -
Background It is not uncommon to observe circulating tumor antigen-specific T lymphocytes in cancer patients despite a lack of significant infiltration and destruction of their tumors....
Search relevance: 90.97 | Views last month: 0 -
Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human...
Search relevance: 86.60 | Views last month: 0 -
The invention concerns new tumor necrosis factor receptor associated factors, designated TRAFs. The new factors are capable of specific association with the intracellular domain of the type 2 TNF...
Search relevance: 86.55 | Views last month: 0 -
Recognition molecules (RM), especially antibodies (A) that bind specifically to the Core-1 (C1) antigen, comprising defined amino acids sequences (1-6) given in the specification and below, are...
Search relevance: 83.48 | Views last month: 0 -
Background The excitatory amino acid domoic acid, a glutamate and kainic acid analog, is the causative agent of amnesic shellfish poisoning in humans. No studies to our knowledge have...
Search relevance: 82.33 | Views last month: 0 -
Tumor necrosis factor-α (TNF-α) is a polypeptide cytokine that has been associated with muscle wasting and weakness in inflammatory disease. Despite its potential importance in muscle pathology,...
Search relevance: 81.95 | Views last month: 1 -
The cellular and molecular mechanisms that are involved in airway hyper-responsiveness are unclear. Current studies suggest that tumor necrosis factor (TNF)-α, a cytokine that is produced in...
Search relevance: 80.89 | Views last month: 0 -
The methods and reagents described in this invention are used to analyze circulating tumor cells, clusters, fragments, and debris. Analysis is performed with a number of platforms, including flow...
Search relevance: 79.06 | Views last month: 0 -
Fusing dendritic cells (DC) and tumor cells (TC) in which the two cell types are mixed; optionally washed; centrifuged, then the pellet taken up in electrofusion medium (EFM) and subjected to...
Search relevance: 77.84 | Views last month: 0 -
Background NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin, has been shown to...
Search relevance: 76.93 | Views last month: 0
