A Generic Pharmacokinetic Model for Quantifying Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals
This data set includes source code files and associated data files that implement a pharmacokinetic (PK) model for lipophilic persistent environmental chemicals (LPECs) that can be used to simulate various exposure scenarios involving pregnant and nursing maternal animals and offspring. The model is described in a manuscript entitled "A Generic Pharmacokinetic Model for Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals" by Kapraun et al.
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Dustin Kapraun",
"hasEmail": "mailto:kapraun.dustin@epa.gov"
}
|
| description | This data set includes source code files and associated data files that implement a pharmacokinetic (PK) model for lipophilic persistent environmental chemicals (LPECs) that can be used to simulate various exposure scenarios involving pregnant and nursing maternal animals and offspring. The model is described in a manuscript entitled "A Generic Pharmacokinetic Model for Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals" by Kapraun et al. |
| distribution |
[
{
"title": "Kapraun2022_LPEC_PK_model.zip",
"mediaType": "application/x-zip-compressed",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524467/Kapraun2022_LPEC_PK_model.zip"
},
{
"title": "Kapraun2022_LPEC_PK_model_instructions.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524467/Kapraun2022_LPEC_PK_model_instructions.pdf"
},
{
"title": "RMCSim_install_instructions.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524467/RMCSim_install_instructions.pdf"
}
]
|
| identifier | https://doi.org/10.23719/1524467 |
| keyword |
[
"Children's Environmental Health",
"Lactational Transfer",
"Lipophilic Persistent Environmental Chemical",
"Pharmacokinetic Model",
"pregnancy"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2022-01-11 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
null
|
| rights |
null
|
| title | A Generic Pharmacokinetic Model for Quantifying Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals |