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data sets for Nano TiO2 & CeO2 effects on BEAS-2B cells
Signaling pathways from IPA: canonical pathways obtained by uploading differentially expressed genes onto IPA to get the corresponding pathways altered by the chemicals.
Figure 4 ABCDHILM ROS final: Excel file with raw data and calculated fold change for the ROS (Deep Red) assay on 8 nanoparticles.
Data files for tables: this file include physical-chemical properties of the 8 NPs (worksheet 1), sizing and zeta potential from zeta sizer (worksheet 2&3) and numbers of differentially expressed genes (DEGs) (worksheet 4).
Data files for figure 5 to 11: physical -chemical properties of the NPs, raw data and calculation for ROS-RNS, 8-oxo-dG, AP sites, endogenous DNA adducts, 4-HNE, and MDA adducts.
This dataset is associated with the following publication:
Thai, S., C. Jones, G. Nelson, B. Vallanat, M. Killius, J. Crooks, w. Ward, C. Blackman, and J. Ross. Differential effects of Nano TiO2 and CeO2 on normal human lung epithelial cells in vitro. Journal of Nanoscience and Nanotechnology. American Scientific Publishers, VALENCIA, CA, USA, 19(11): 6907-6923, (2019).
Complete Metadata
| accessLevel | public |
|---|---|
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"fn": "Sheau-Fung Thai",
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|
| description | Signaling pathways from IPA: canonical pathways obtained by uploading differentially expressed genes onto IPA to get the corresponding pathways altered by the chemicals. Figure 4 ABCDHILM ROS final: Excel file with raw data and calculated fold change for the ROS (Deep Red) assay on 8 nanoparticles. Data files for tables: this file include physical-chemical properties of the 8 NPs (worksheet 1), sizing and zeta potential from zeta sizer (worksheet 2&3) and numbers of differentially expressed genes (DEGs) (worksheet 4). Data files for figure 5 to 11: physical -chemical properties of the NPs, raw data and calculation for ROS-RNS, 8-oxo-dG, AP sites, endogenous DNA adducts, 4-HNE, and MDA adducts. This dataset is associated with the following publication: Thai, S., C. Jones, G. Nelson, B. Vallanat, M. Killius, J. Crooks, w. Ward, C. Blackman, and J. Ross. Differential effects of Nano TiO2 and CeO2 on normal human lung epithelial cells in vitro. Journal of Nanoscience and Nanotechnology. American Scientific Publishers, VALENCIA, CA, USA, 19(11): 6907-6923, (2019). |
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| identifier | https://doi.org/10.23719/1502468 |
| keyword |
[
"DNA damage assays",
"Reactive oxygen species",
"engineered nanomaterials",
"signaling pathways analysis",
"transcriptomics"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2018-07-09 |
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"name": "U.S. EPA Office of Research and Development (ORD)",
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|
| references |
[
"https://doi.org/10.1166/jnn.2019.16737"
]
|
| rights |
null
|
| title | data sets for Nano TiO2 & CeO2 effects on BEAS-2B cells |
