Effects of metformin and its metabolite guanylurea on fathead minnow (Pimephales promelas) reproduction
Data associated with exposures of fathead minnows to varying concentrations of metformin and/or guanylurea. Includes three individual studies: ex vivo steroidogenesis assay, 96 h time course assay, 23 d reproduction assay.
This dataset is associated with the following publication:
Blackwell, B., G. Ankley, A. Biales, J. Cavallin, A. Cole, T. Collette, D. Ekman, R. Hofer, W. Huang, K. Jensen, M. Kahl, A. Kittelson, S. Romano, M. See, Q. Teng, C. Tilton, and D. Villeneuve. Effects of Metformin and its Metabolite Guanylurea on Fathead Minnow (Pimephales promelas) Reproduction (FY22 Manuscript). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 41(11): 2708-2720, (2022).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Brett Blackwell",
"hasEmail": "mailto:blackwell.brett@epa.gov"
}
|
| description | Data associated with exposures of fathead minnows to varying concentrations of metformin and/or guanylurea. Includes three individual studies: ex vivo steroidogenesis assay, 96 h time course assay, 23 d reproduction assay. This dataset is associated with the following publication: Blackwell, B., G. Ankley, A. Biales, J. Cavallin, A. Cole, T. Collette, D. Ekman, R. Hofer, W. Huang, K. Jensen, M. Kahl, A. Kittelson, S. Romano, M. See, Q. Teng, C. Tilton, and D. Villeneuve. Effects of Metformin and its Metabolite Guanylurea on Fathead Minnow (Pimephales promelas) Reproduction (FY22 Manuscript). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 41(11): 2708-2720, (2022). |
| distribution |
[
{
"title": "SciHub_metformin effects_final.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526538/SciHub_metformin%20effects_final.xlsx"
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|
| identifier | https://doi.org/10.23719/1526538 |
| keyword |
[
"aquatic toxicity",
"endocrine disruption",
"pharmaceuticals",
"reproduction"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2022-07-01 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1002/etc.5450"
]
|
| rights |
null
|
| title | Effects of metformin and its metabolite guanylurea on fathead minnow (Pimephales promelas) reproduction |
