Found 93 datasets matching "endocrine disruption".
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This data release presents chemical and biological results from investigations of water quality, fish endocrine disruption, and emergent insects in the Shenandoah River Watershed (Virginia and...
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Disruption of thyroid hormone signaling is a form of endocrine disruption that is of concern to both human health and ecosystems. Research is being conducted to define the biological targets...
Search relevance: 112.80 | Views last month: 0 -
In response to various legislative mandates the United States Environmental Protection Agency (USEPA) formed its Endocrine Disruptor Screening Program (EDSP), which in turn, implemented a tiered...
Search relevance: 109.69 | Views last month: 0 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 102.23 | Views last month: 1 -
Decades of poor reproductive success and young-of-the-year recruitment, in addition to adult mortality, has led to a decline in the smallmouth bass (SMB) population in subwatersheds of the Potomac...
Search relevance: 88.83 | Views last month: 0 -
In 2016, smallmouth bass were collected from three sites in the Lake Erie drainage in Erie County, Pennsylvania and an out-of-basin site in the Allegheny River drainage in order to assess...
Search relevance: 80.25 | Views last month: 0 -
A liquid chromatogrpahy mass spectrometry (LC-MS) method was developed for the analysis of 13 endogenous steroids. The method was validated using both fish plasma and fish holding water. The...
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Liquid chromatography tandem mass spectrometry allows for the measurement of steroid hormone suites in the blubber of marine mammals. By combining this technology with remote biopsy collection,...
Search relevance: 67.46 | Views last month: 0 -
Liquid chromatography tandem mass spectrometry allows for the measurement of steroid hormone suites in the blubber of marine mammals. By combining this technology with remote biopsy collection,...
Search relevance: 67.46 | Views last month: 0 -
This is a collection of over 290,000 hazard data records compiled for the Alternatives Assessment Dashboard. The hazard data includes records for human health, ecotoxicity, and fate. The human...
Search relevance: 63.33 | Views last month: 2 -
Baseline fish health information on pallid sturgeon and bull trout or appropriate surrogate species (shovelnose sturgeon, cutthroat trout, mountain whitefish) in critical habitats with elevated...
Search relevance: 59.72 | Views last month: 0 -
The data presented include concentrations of 122 organic, 23 inorganic constituents, and estrogenicity in water collected from 13 off-stream non-point source sites (natural and created wetlands)...
Search relevance: 58.68 | Views last month: 0 -
Excel spreadsheet that contains the raw fecundity data used to conduct power simulations specific to the MEOGRT reproductive assessment. This dataset is associated with the following...
Search relevance: 51.33 | Views last month: 0 -
Supplementary materials for "Olker JH, Korte JJ, Haselman JT, Hornung MW, Degitz SJ. Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase. Aquat Toxicol....
Search relevance: 51.31 | Views last month: 0 -
Microarray experiments examined in the study. This dataset is associated with the following publication: Rooney, J., N. Ryan, J. Liu, R. Houtman, R. van Beuningen, J. Hsieh, G. Chang, S. Chen,...
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Data associated with exposures of fathead minnows to varying concentrations of metformin and/or guanylurea. Includes three individual studies: ex vivo steroidogenesis assay, 96 h time course...
Search relevance: 50.99 | Views last month: 0 -
Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology...
Search relevance: 50.57 | Views last month: 0 -
This dataset contains in vitro and in vivo biochemical and apical (i.e., growth/development) data pertaining to iodotyrosine deiodinase inhibition in the African clawed frog (Xenopus laevis)....
Search relevance: 50.22 | Views last month: 0 -
These data are represented in the tables and graphs in the journal article, Antiandrogenic effects following multiple life stage exposure to the fungicide prochloraz in Xenopus laevis by JT...
Search relevance: 50.15 | Views last month: 0 -
Triclocarban (TCC) is a widely used antimicrobial agent that is routinely detected in surface waters. The present study was designed to examine TCC’s efficacy and mode of action as a reproductive...
Search relevance: 49.84 | Views last month: 1
