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Fetal and Postnatal Cortical Thyroid Hormone Levels and Bioindicators
thyroid hormones in serum and in brain were measured in fetal and neonatal rat cortex after graded levels of a thyroid hormone synthesis inhibitor were administered to pregnant rat dams. A number of gene targets were assessed to look for measures of thyroid hormone action in these same tissues.
This dataset is associated with the following publication:
OShaughnessy, K., C. Wood, R. Ford, P. Kosian, M. Hotchkiss, S. Degitz, and M. Gilbert. Thyroid hormone disruption in the fetal and neonatal rat: Predictive hormone measures and bioindicators of hormone action in the developing cortex- ToxSci. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163-179, (2018).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Mary Gilbert",
"hasEmail": "mailto:gilbert.mary@epa.gov"
}
|
| description | thyroid hormones in serum and in brain were measured in fetal and neonatal rat cortex after graded levels of a thyroid hormone synthesis inhibitor were administered to pregnant rat dams. A number of gene targets were assessed to look for measures of thyroid hormone action in these same tissues. This dataset is associated with the following publication: OShaughnessy, K., C. Wood, R. Ford, P. Kosian, M. Hotchkiss, S. Degitz, and M. Gilbert. Thyroid hormone disruption in the fetal and neonatal rat: Predictive hormone measures and bioindicators of hormone action in the developing cortex- ToxSci. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163-179, (2018). |
| distribution |
[
{
"title": "OShaughnessyetalScienceHub.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1420050/OShaughnessyetalScienceHub.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1420050 |
| keyword |
[
"brain developoment",
"molecular markers",
"thyroid"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2018-02-09 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1093/toxsci/kfy190"
]
|
| rights |
null
|
| title | Fetal and Postnatal Cortical Thyroid Hormone Levels and Bioindicators |
