Found 97 datasets matching "thyroid".
-
This dataset contains results from rodent study. Thyroid hormones and brain endpoints are reported for pregnant rat dams and progeny on gestational day 20 following drinking water exposure to the...
Search relevance: 144.66 | Views last month: 1 -
This dataset was generated to support parameterization of a larval amphibian thyroid axis computational model. Specifically, plasma iodine levels were determined not only to inform a concentration...
Search relevance: 136.40 | Views last month: 0 -
thyroid hormones in serum and in brain were measured in fetal and neonatal rat cortex after graded levels of a thyroid hormone synthesis inhibitor were administered to pregnant rat dams. A number...
Search relevance: 133.88 | Views last month: 0 -
How to access data for "Decrane R, Stoker T, Murr A, Ford J, El-Masri H. Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen using in vitro data,...
Search relevance: 130.69 | Views last month: 1 -
The objective of this study was to develop a medium-throughput organotypic screening assay comprised of reconstructed human thyroid microtissues to quantitatively evaluate the disruptive effects...
Search relevance: 128.21 | Views last month: 1 -
Serum and brain thyroid hormone measurements in rat brain. This dataset is associated with the following publication: Gilbert, M., J. Ford, C. Riutta, K. OShaughnessy, and P.A. Kosian. Reducing...
Search relevance: 127.71 | Views last month: 0 -
Adequate levels of thyroid hormones (TH) are needed for proper brain development, deficiencies may lead to adverse neurological outcomes in humans and animal models. Environmental chemicals have...
Search relevance: 127.09 | Views last month: 3 -
Dataset for Foley et al. 'Technical evaluation and standardization of the human thyroid microtissue assay'; Toxicological Sciences, Vol 199, Issue 1, pg 89-107, kfae014 May 2024. DOI...
Search relevance: 126.86 | Views last month: 0 -
thyroid hormone from serum of rats exposed to goitrogen. Morphometry in brain. Behavioral data. This dataset is associated with the following publication: OShaughnessy, K., P. Kosian, J. Ford,...
Search relevance: 118.77 | Views last month: 0 -
Biomarker Image Cytometry. The cell-level frequency of NK2 Homeobox 1 (NKX2-1), Keratin 7 (KRT7), and Thyroglobulin (TG) protein staining were quantitatively evaluated by high-content imaging...
Search relevance: 118.45 | Views last month: 0 -
Raw data accompanying "Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain". This dataset is associated with the following...
Search relevance: 117.51 | Views last month: 0 -
Background Mefloquine is a clinically important antimalaria drug, which is often not well tolerated. We critically reviewed 516 published case reports of mefloquine adverse effects, to...
Search relevance: 116.96 | Views last month: 0 -
This dataset includes the results of a long term adult female rat oral exposure to triclosan and includes hormone, estrous cyclicity, thyroid histology and liver gene expression data. This...
Search relevance: 116.70 | Views last month: 4 -
This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the two chemicals tested,...
Search relevance: 116.35 | Views last month: 1 -
Severe thyroid hormone (TH) deprivation during development impairs neurogenesis throughout the brain. The hippocampus also maintains a capacity for neurogenesis throughout life which is reduced in...
Search relevance: 111.76 | Views last month: 1 -
Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro screening assays through...
Search relevance: 111.76 | Views last month: 1 -
behavioral measures of learning and memory in adult offspring of rats treated with thyroid hormone synthesis inhibitor, propylthiouracil. Electrophysiological measures of 'memory' in form of...
Search relevance: 111.05 | Views last month: 0 -
Background Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the mechanism by which thyroid...
Search relevance: 109.79 | Views last month: 0 -
Data pertaining to a NIS-expressing cell line, hNIS-HEK293T-EPA, and its screening capabilities for determining inhibitors of NIS-mediated iodide uptake. This dataset is associated with the...
Search relevance: 107.44 | Views last month: 0 -
The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database containing all literature that was...
Search relevance: 107.39 | Views last month: 0
