Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines
Biomarker Image Cytometry. The cell-level frequency of NK2 Homeobox 1 (NKX2-1), Keratin 7 (KRT7), and Thyroglobulin (TG) protein staining were quantitatively evaluated by high-content imaging across huThyrEC cell line variants (1-4) in two medium formulations (huThyrEC and h7H) for verification of thyroid follicular epithelial cell enrichment. Data are the % positive expression frequency (mean ± SD) of two replicates.
This dataset is associated with the following publication:
Hopperstad, K., T. Truschel, T. Wahlicht, W. Stewart, A. Eicher, T. May, and C. Deisenroth. Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines. Applied In Vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 7(2): 39-49, (2021).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Thomas Knudsen",
"hasEmail": "mailto:knudsen.thomas@epa.gov"
}
|
| description | Biomarker Image Cytometry. The cell-level frequency of NK2 Homeobox 1 (NKX2-1), Keratin 7 (KRT7), and Thyroglobulin (TG) protein staining were quantitatively evaluated by high-content imaging across huThyrEC cell line variants (1-4) in two medium formulations (huThyrEC and h7H) for verification of thyroid follicular epithelial cell enrichment. Data are the % positive expression frequency (mean ± SD) of two replicates. This dataset is associated with the following publication: Hopperstad, K., T. Truschel, T. Wahlicht, W. Stewart, A. Eicher, T. May, and C. Deisenroth. Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines. Applied In Vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 7(2): 39-49, (2021). |
| distribution |
[
{
"title": "AIVT_EPA-InSCREENeX_Tables_All_v1.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1520918/AIVT_EPA-InSCREENeX_Tables_All_v1.xlsx"
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|
| identifier | https://doi.org/10.23719/1520918 |
| keyword |
[
"endocrine toxicology",
"in vitro toxicology",
"organotypic culture model",
"thyroid",
"tipping points",
"vEmbryo",
"virtual embryo",
"virtual tissues"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2020-09-11 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1089/aivt.2020.0027"
]
|
| rights |
null
|
| title | Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines |
