Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption
The data set consists of the following:
1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network.
2) A literature database containing all literature that was cited in the main document. The database also contains additional references that were not explicitly cited in the associated manuscript.
3) R code used for the analyses and visualizations
4) Detailed results from the SeqAPASS tool.
This dataset is associated with the following publication:
Haigis, A., L. Vergauwen, C. LaLone, D. Villeneuve, J. O'Brien, and D. Knapen. Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 195(1): 1-27, (2023).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Daniel Villeneuve",
"hasEmail": "mailto:villeneuve.dan@epa.gov"
}
|
| description | The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database containing all literature that was cited in the main document. The database also contains additional references that were not explicitly cited in the associated manuscript. 3) R code used for the analyses and visualizations 4) Detailed results from the SeqAPASS tool. This dataset is associated with the following publication: Haigis, A., L. Vergauwen, C. LaLone, D. Villeneuve, J. O'Brien, and D. Knapen. Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 195(1): 1-27, (2023). |
| distribution |
[
{
"title": "https://clowder.edap-cluster.com/datasets/6495afabe4b08a6b394f8bf2?space=62e913afe4b055edffc06b16",
"accessURL": "https://clowder.edap-cluster.com/datasets/6495afabe4b08a6b394f8bf2?space=62e913afe4b055edffc06b16"
},
{
"title": "R-files.zip",
"mediaType": "application/zip",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529155/R-files.zip"
},
{
"title": "SeqAPASS-details.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529155/SeqAPASS-details.xlsx"
},
{
"title": "literature-database.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529155/literature-database.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1529155 |
| keyword |
[
"Adverse Outcome Pathways (AOPs)",
"cross-species extrapolation",
"endocrine disruption",
"thyroid"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html |
| modified | 2023-06-23 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1093/toxsci/kfad063"
]
|
| rights |
null
|
| title | Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption |
