The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish
The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish". The data set includes:
1) Effects of three test chemicals on thyroperoxidase enzyme activity
2) Effects of three test chemicals on deiodinase enzyme activity
3) Thyroid hormone (T3 and T4) concentrations measured in exposed larvae
4) Measures of posterior and anterior swimbladder chamber inflation and surface areas.
5) Data on swimming behavior (distance) of exposed fish.
6) Measured concentrations of the test chemicals in the test media and tissues.
This dataset is associated with the following publication:
Stinckens, E., L. Vergauwen, B. Blackwell, G. Ankley, D. Villeneuve, and D. Knapen. Effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 54(10): 6213-6223, (2020).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Daniel Villeneuve",
"hasEmail": "mailto:villeneuve.dan@epa.gov"
}
|
| description | The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish". The data set includes: 1) Effects of three test chemicals on thyroperoxidase enzyme activity 2) Effects of three test chemicals on deiodinase enzyme activity 3) Thyroid hormone (T3 and T4) concentrations measured in exposed larvae 4) Measures of posterior and anterior swimbladder chamber inflation and surface areas. 5) Data on swimming behavior (distance) of exposed fish. 6) Measured concentrations of the test chemicals in the test media and tissues. This dataset is associated with the following publication: Stinckens, E., L. Vergauwen, B. Blackwell, G. Ankley, D. Villeneuve, and D. Knapen. Effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 54(10): 6213-6223, (2020). |
| distribution |
[
{
"title": "tpo-dio-anterior-data-2019-10-31.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518536/tpo-dio-anterior-data-2019-10-31.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1518536 |
| keyword |
[
"adverse outcome pathway",
"aquatic ecosystems",
"ecotoxicology",
"endocrine disruption",
"screening and prioritization"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2020-04-16 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1021/acs.est.9b07204"
]
|
| rights |
null
|
| title | The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish |
