Xenpous leavis deiodinase type 3 enzyme activity characterization and chemical screening data
Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast chemicals against this enzyme.
This dataset is associated with the following publication:
Mayasich, S., J. Korte, J. Denny, P. Hartig, J. Olker, P. Degoey, J. O'Flanagan, S. Degitz, and M. Hornung. Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 73: 105141, (2021).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Michael Hornung",
"hasEmail": "mailto:hornung.michael@epa.gov"
}
|
| description | Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast chemicals against this enzyme. This dataset is associated with the following publication: Mayasich, S., J. Korte, J. Denny, P. Hartig, J. Olker, P. Degoey, J. O'Flanagan, S. Degitz, and M. Hornung. Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 73: 105141, (2021). |
| distribution |
[
{
"title": "200714_Mayasich_et_al_Xldio3 screening data.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504033/200714_Mayasich_et_al_Xldio3%20screening%20data.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1504033 |
| keyword |
[
"Enzyme activity",
"Xenopus",
"deiodinase",
"thyroid"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-06-19 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1016/j.tiv.2021.105141"
]
|
| rights |
null
|
| title | Xenpous leavis deiodinase type 3 enzyme activity characterization and chemical screening data |
