Found 26 datasets matching filters.
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The attached zip file contains all of the source data, intermediate outputs and R-scripts used to calculate the tipping points reported in the Frank et al manuscript. This dataset is associated...
Search relevance: 1.00 | Views last month: 5 | Published on: 2025-08-02 -
The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/toxics10050256/s1. Figure S1, Effect of DMSO on Light/Dark Locomotor Activity; Figure S2, Time...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
This dataset contains results from rodent study. Thyroid hormones and brain endpoints are reported for pregnant rat dams and progeny on gestational day 20 following drinking water exposure to the...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Perchlorate is an environmental contaminant that interferes with iodine uptake via the NIS transporter into the thyroid gland, reducing thyroid hormone (TH) synthesis. As adequate supplies of TH...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This data file contains the full raw parameter data for the 86 compounds tested in the developmental MEA assay, as well as Area Under the Curve (AUC) calculations and plate normalized data.
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Data on morphology of rat and human neurons in cell culture. This dataset is associated with the following publication: Druwe, I., T. Freudenrich , K. Wallace , T. Shafer , and W. Mundy....
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis, viability, neurite outgrowth,...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Thyroid hormones status, brain molecular and structural changes, and neurobehavioral impairments following maternal exposure to perchlorate in a rodent pregnancy model. This dataset is...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Severe thyroid hormone (TH) deprivation during development impairs neurogenesis throughout the brain. The hippocampus also maintains a capacity for neurogenesis throughout life which is reduced in...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on parameters of network development...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Serum and brain thyroid hormone measurements in rat brain. This dataset is associated with the following publication: Gilbert, M., J. Ford, C. Riutta, K. OShaughnessy, and P.A. Kosian. Reducing...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Raw data accompanying "Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain". This dataset is associated with the following...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Raw data to accompanying manuscript "The Pollutant Perfluorohexane Sulfonate (PFHxS) Reduces Serum Thyroxine but Does Not Alter Thyroid Hormone Action in the Postnatal Rat Brain". This dataset...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Structural defects in the rat brain associated with maternal exposure to ammonium perchlorate accompanied reductions in circulating levels of thyroid hormone in the dam and the fetus. The...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Data used to generate figures shown in Phelps et al. This dataset is associated with the following publication: Phelps, D., N. Brinkman, S. Keely, E. Anneken, T. Catron, D. Betancourt, C. Wood,...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Further details on 5 files are found in overview tab of each one. All data sets contain transcriptomic data from Biospyder run in March 2025. 1. "Biospyder M0516..." Tissue is forebrain of GD20...
Search relevance: 1.00 | Views last month: 0 | Published on: 2026-02-27 -
Supplementary data for "A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays". This dataset is associated with the following...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-11-06 -
Table of contents Table S1 DNT inventory List of sources and associated data collected for the development of the Bayesian hierarchical model. Table S2 Data...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K.,...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Contains values from pbpk models for each study on n-butanol effects. This dataset is associated with the following publication: Segal, D., A. Bale, L. Phillips, A. Sasso, P. Schlosser, C....
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02