Found 42 datasets matching filters.
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To better understand the transport of neonicotinoid insecticides into the Great Lakes, monthly samples (October 2015-September 2016) were collected from 10 tributaries to the Great Lakes, USA. At...
Search relevance: 1.00 | Views last month: 4 | Published on: 2025-08-02 -
Ongoing honey bee colony losses are of significant international concern because of the essential role these insects play in pollinating many high nutrient crops, such as fruits, vegetables, and...
Search relevance: 1.00 | Views last month: 3 | Published on: 2025-08-02 -
The dataset includes survival of control, control injected, and CRISPR/Cas9 injected embryos as well as percent efficiency of insertion/deletion mutation formation for the three different CRISPR...
Search relevance: 1.00 | Views last month: 3 | Published on: 2025-08-02 -
Fathead minnows (Pimephales promelas) were exposed to 100 ug/L indomethacin, 200 ug/L ibuprofen, or 20 ug/L celecoxib for 96 h. Effects on cycloxygenase enzyme activity in ovary, prostaglandin...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
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Datasets included in the entry are Results from the US Environmental Protection Agency Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool and from the molecular modeling...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
Dataset for "Pronschinske, M.A., Corsi, S.R., DeCicco, L.A., Furlong, E.T., Ankley, G.T., Blackwell, B.R., Villeneuve, D.L., Lenaker, P.L. and Nott, M.A. (2022), Prioritizing Pharmaceutical...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
The datafile contains data associated with analytical chemistry, fish gene expression, in vitro bioassays, chemical prioritization, and Attagene data for surface water monitoring and caged fish...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Prioritization of chemicals was performed on two Areas of Concerns in the Great Lakes An integrated risk surveillance and monitoring approach was applied Bio-effect prediction methodologies were...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Triclocarban (TCC) is a widely used antimicrobial agent that is routinely detected in surface waters. The present study was designed to examine TCC’s efficacy and mode of action as a reproductive...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
In September, 2015, a water sample was collected downstream of a major metropolitan waste water treatment plant that discharges to the South Platte River, Colorado, USA. The grab sample, 1L, was...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Previous work identified a ‘cytotoxic burst’ (CTB) phenomenon wherein large numbers of the ToxCast assays begin to respond at or near test chemical concentrations that elicit cytotoxicity, and a...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase inhibition on anterior swim...
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The data set provides a set of txt files and cytoscape files that were used to construct the example AOP networks included in the paper. Additionally, a supplementary table file provides all the...
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Water-borne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs), and polar organic chemical integrative...
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The present study investigated whether inhibition of deiodinase, the enzyme which converts thyroxine (T4) to the more biologically-active form, 3,5,3'-triiodothyronine (T3), would impact inflation...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Disruption of thyroid hormone signaling is a form of endocrine disruption that is of concern to both human health and ecosystems. Research is being conducted to define the biological targets...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Data used in the creation of each figure and table cited in Doering et al. (2019; DOI: 10.1021/acs.est.9b02606) are provided. This dataset is associated with the following publication: Doering,...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02