• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs,...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The present paper aims at studying the role of B7/CD28 interaction and related cytokine production in the immunological changes after exposure to different doses of ionizing...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The origin and role of IL-17, a T-cell derived cytokine, in cartilage and bone destruction during rheumatoid arthritis (RA) remain to be clarified. In human ex vivo models, addition of IL-17...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Introduction Hemofiltration may modulate the inflammatory response in sepsis through a variety of mechanisms. We sought to distinguish clearance from adsorption as the principal...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression is poorly understood, but...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Human resistance to re-infection with S. mansoni is correlated with high levels of anti-soluble adult worm antigens (SWAP) IgE. Although it has been shown that IL-4 and IL-5...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background In asthma and other allergic disorders, the activation of mast cells by IgE and antigen induces the cells to release histamine and other mediators of inflammation, as well as...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Early changes in transcriptional profiles of circulating mononuclear cells were compared with those occurring within the microenvironment of melanoma metastases following systemic IL-2...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6 signaling and...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-05-08T00:00:00.000+00:00

This EnviroAtlas dataset shows the Chicago, IL EnviroAtlas community boundary. It represents the outside edge of all the block groups included in the EnviroAtlas Community. This dataset was...

• Organization: Department of Agriculture
• Updated: 2024-02-08

The data herein is related to the research article entitled "Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex", where...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-05-08T00:00:00.000+00:00

This EnviroAtlas dataset is the base layer for the Chicago, IL EnviroAtlas area. The block groups are from the US Census Bureau and are included/excluded based on EnviroAtlas criteria described in...

• Organization: Department of the Interior
• Updated: 2020-08-14T00:00:00Z

ADCP data were collected on November 4, 2015 at the confluence of the Illinois River and Fox River near Ottawa, IL using a Teledyne Rio Grande 1200 kHz Acoustic Doppler Current Profiler with...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Recent studies have described the spontaneous development of arthritis or vasculitis in IL-1 receptor antagonist (IL-1Ra) knockout mice bred on specific and different genetic backgrounds....

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• Organization: Lake County, Illinois
• Updated: 2022-03-23T21:23:28.000Z

Link to Lake County, IL website.

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Interleukin-1 receptor antagonist (IL-1Ra) is a natural IL-1 inhibitor possessing anti-inflammatory properties. IL-1Ra is produced as different isoforms, one secreted (sIL-1Ra) and three...

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• Organization: Lake County, Illinois
• Updated: 2022-03-23T21:23:25.000Z

Link to Lake County, IL website.

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• arcgis geoservices rest api

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

An excess of the proinflammatory substance IL-18 is present in joints of patients with rheumatoid arthritis (RA), and expression of IL-18 receptor (IL-18R) regulates IL-18 bioactivity in various...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are considered to be master cytokines in chronic, destructive arthritis. Therapeutic approaches in rheumatoid arthritis (RA) patients have so...

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