Found 53 datasets matching "In vitro assay".
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This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the two chemicals tested,...
Search relevance: 186.01 | Views last month: 1 -
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
Search relevance: 157.60 | Views last month: 3 -
the data set contains the figures and tables from the publication in addition to the means, standard errors of the mean and the sample sizes used in each group for every experiment. the data set...
Search relevance: 137.53 | Views last month: 1 -
Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house...
Search relevance: 119.45 | Views last month: 0 -
The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the ToxCast Phase 1_v2, Phase 2, and...
Search relevance: 107.94 | Views last month: 0 -
A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC) were examined for their ability to...
Search relevance: 99.88 | Views last month: 0 -
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis, viability, neurite outgrowth,...
Search relevance: 67.01 | Views last month: 1 -
Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol...
Search relevance: 65.70 | Views last month: 0 -
This publication provides an optimized UGT assay for trout liver S9 fractions which can be used to perform in vitro-in vivo extrapolations of measured UGT activity. This dataset is associated...
Search relevance: 64.54 | Views last month: 1 -
Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology...
Search relevance: 64.01 | Views last month: 0 -
In vitro and in vivo data for the estrogen receptor. The in vivo data is for binding, agonism, and antagonism. The in vivo data is from mouse uterotropic assay data. The following columns are...
Search relevance: 60.67 | Views last month: 1 -
A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
Search relevance: 60.67 | Views last month: 0 -
This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression...
Search relevance: 60.52 | Views last month: 0 -
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput...
Search relevance: 59.59 | Views last month: 1 -
This study evaluated two anti-angiogenic agents, 5HPP-33 and TNP-470, across the ToxCastDB HTS assay platform and anchored the results to complex in vitro functional assays: the rat aortic explant...
Search relevance: 58.45 | Views last month: 0 -
Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints. Table S2. Agreement with OECD reference AR agonists. Table S3. Agreement with OECD reference ER...
Search relevance: 57.99 | Views last month: 0 -
These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used. This dataset is associated...
Search relevance: 57.81 | Views last month: 0 -
Bioaccessibility values for fipronil determined using 37 paired soil and dust samples. Values for the physicochemical properties of the soils and dusts used to model the bioaccessibility data....
Search relevance: 53.90 | Views last month: 0 -
In crude-oil-contaminant plumes the dissolved organic carbon (DOC) is mainly hydrocarbon degradation intermediates only partly quantified by the diesel range total petroleum hydrocarbon (TPHd)...
Search relevance: 52.25 | Views last month: 0 -
The datasets provide physicochemical endpoint values (volumes, pH) for exhaled breath condensate collected with spontaneous breathing and "controlled" breathing patterns. The controlled breathing...
Search relevance: 51.41 | Views last month: 0
