Found 25 datasets matching "In vitro metabolism".
-
Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays' published in Toxicology, Vol 517,...
Search relevance: 210.73 | Views last month: 0 -
The current study constitutes the first report of the metabolism of imidacloprid and acetamiprid in rainbow trout. Formation of respective metabolites 5-hydroxy-imidacloprid and...
Search relevance: 201.03 | Views last month: 0 -
Files contain summary reports of chemical and Mass Spectrometry raw and analyzed data used as basis for plot generation and text discussions in the Cyclic phenone metabolism manuscript. File...
Search relevance: 187.60 | Views last month: 0 -
Thiacloprid (THI) is a neonicotinoid insecticide of interest to the USEPA due to its low absorption by crops, greater distribution into the surrounding areas, and potential for adverse effect to...
Search relevance: 108.50 | Views last month: 0 -
The purpose of this study was to compare two in vitro systems, cryopreserved trout hepatocytes and trout liver S9 fractions, used to predict in vivo levels of biotransformation in fish. This...
Search relevance: 70.93 | Views last month: 0 -
Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
Search relevance: 68.37 | Views last month: 0 -
This dataset, presented as an Excel spreadsheet, contains all data presented as figures and tables in an article by Nichols et al, entitled "In vitro-in vivo extrapolation of hepatic...
Search relevance: 60.78 | Views last month: 1 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 55.66 | Views last month: 6 -
Data sets in the context of this project are the model files, model input parameter sets, and data generated at the US EPA/ORD/National Health and Environmental Effects Research Laboratory that...
Search relevance: 52.98 | Views last month: 0 -
Background Setting of graded levels of a protein for in vivo studies by controlled gene expression has inconveniences, and we here explore the use of the t-degron technique instead. ...
Search relevance: 51.67 | Views last month: 0 -
This data includes metabolite predictions for in vitro inactive chemicals, predictions of those metabolite's estrogen receptor binding activity, in vitro and in silico information regarding parent...
Search relevance: 51.45 | Views last month: 0 -
This paper described development of an in vitro/in vivo model that accounts for first pass clearance effects. The model details are contained in the supporting information for the paper. This...
Search relevance: 50.52 | Views last month: 0 -
Dataset for "Crizer, D.M.; Rice, J.R.; Smeltz, M.G.; Lavrich, K.S.; Ravindra, K.; Wambaugh, J.F.; DeVito, M.; Wetmore, B.A. In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl...
Search relevance: 49.96 | Views last month: 1 -
Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is...
Search relevance: 49.43 | Views last month: 1 -
Taking advantage of the flexibility and control only attained through application of an in vitro platform, we were able develop a model of small intestinal gut microbiota that we used to address...
Search relevance: 47.45 | Views last month: 0 -
Gene expression data from the Fluidigm qRT-PCR arrays was analyzed in R (v3.6.1; R Foundation for Statistical Computing, 2019). Prior to processing through the tcpl package, each qRT-PCR primer...
Search relevance: 46.96 | Views last month: 2 -
exposure_experiment.csv: time: length of time that amphibian was exposed to that pesticide in hours. parent: is the active ingredient that the amphibian was exposed to. analyte: either the...
Search relevance: 44.38 | Views last month: 0 -
Dataset consists of 2 main files as follows: 1. All main and Supplemental MS final figures used for manuscript preparation for better viewing (pdf file). Figures are copies of raw or analyzed...
Search relevance: 43.87 | Views last month: 0 -
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation i.e. simulated mg* to 2g*) and...
Search relevance: 42.06 | Views last month: 0 -
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation i.e. simulated mg* to 2g*) and...
Search relevance: 41.13 | Views last month: 0
