Found 25 datasets matching "cytochrome P450".
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Dataset for S. Sakamuru, et al., 'Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes' published in Int'l Journal of Molecular Sciences, DOI...
Search relevance: 257.10 | Views last month: 0 -
Background The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for...
Search relevance: 170.87 | Views last month: 0 -
Background Nasopharyngeal carcinoma (NPC) is a rare tumor in most parts of the world but occurs at relatively high frequency among people of Chinese descent. The cytochrome P450 2E1...
Search relevance: 162.28 | Views last month: 0 -
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
Search relevance: 149.19 | Views last month: 1 -
The raw values used to create figures 1 and 2 and table 3. This dataset is associated with the following publication: Liu, J., Y. Lu, C. Corton, and C. Klaassen. Expression of cytochrome P450...
Search relevance: 141.88 | Views last month: 0 -
Background Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related genes, in species with...
Search relevance: 111.24 | Views last month: 0 -
Most of the data illustrates the effects that some e-cigarette flavoring agents, as well as some of the chemical components of those flavoring agents, directly have on the cytochrome P450 2A6...
Search relevance: 74.20 | Views last month: 0 -
This ScienceHub dataset provides characterization data for a pooled sample of trout liver S9 fractions that was used to study the in vitro intrinsic clearance of selected cationic surfactants. ...
Search relevance: 64.15 | Views last month: 0 -
The risks and benefits of stopping antiretroviral therapy in patients admitted to the ICU are largely unmeasured. In many cases therapy has to be stopped, as parenteral preparations are...
Search relevance: 62.20 | Views last month: 0 -
A honey bee queen ability to produce eggs is critical to the function of a colony, yet little is known regarding the effects of stress on oviposition or the physiological processes underpinning...
Search relevance: 62.06 | Views last month: 2 -
A novel nuclear receptor, termed the steroid and xenobiotic receptor (SXR), a broad-specificity sensing receptor that is a novel branch of the nuclear receptor superfamily, has been discovered....
Search relevance: 61.68 | Views last month: 0 -
The objective of this study was to develop an approach to retrofit existing HTS assays with hepatic metabolism. The Alginate Immobilization of Metabolic Enzymes (AIME) platform encapsulates...
Search relevance: 58.98 | Views last month: 1 -
Dataset for Sakamuru, S., Ma, D., Pierro, J. D., Baker, N. C., Kleinstreuer, N., Cali, J. J., Knudsen, T. B., & Xia, M. (2024). Development and validation of CYP26A1 inhibition assay for...
Search relevance: 56.11 | Views last month: 0 -
The ascomycete fungus Cryphonectria parasitica is the causal agent of chestnut blight disease. This deadly fungal pathogen was introduced into North America from Asia before the turn of the 20th...
Search relevance: 52.95 | Views last month: 1 -
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
Search relevance: 52.66 | Views last month: 0 -
Background During apoptosis, Ca2+-dependent events participate in the regulation of intracellular and morphological changes including phosphatidylserine exposure in the exoplasmic...
Search relevance: 48.19 | Views last month: 0 -
This data contains information specifically for the Arctic Nearshore Impact Monitoring in the Development Area (ANIMIDA 1999 - 2002) and continuation of Arctic Nearshore Impact Monitoring in the...
Search relevance: 48.16 | Views last month: 0 -
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends not on genomic...
Search relevance: 47.24 | Views last month: 3 -
Final Data SeqAPASS v3.0.zip contains datasets from Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool versions 3.0 for all 497 proteins evaluated using Level 1 (primary...
Search relevance: 47.24 | Views last month: 0
