Found 18 datasets matching "endocrine disrupting chemicals".
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Intersex in small- and largemouth bass has been observed in the upper Chesapeake Bay Watershed since 2003. This observation is indicative of exposure to estrogenic endocrine disrupting chemicals....
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Disruption of thyroid hormone signaling is a form of endocrine disruption that is of concern to both human health and ecosystems. Research is being conducted to define the biological targets...
Search relevance: 82.29 | Views last month: 0 -
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
Search relevance: 80.94 | Views last month: 2 -
A liquid chromatogrpahy mass spectrometry (LC-MS) method was developed for the analysis of 13 endogenous steroids. The method was validated using both fish plasma and fish holding water. The...
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There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
Search relevance: 79.70 | Views last month: 1 -
This paper presents data from studies performed to satisfy test orders from the US EPA’s Endocrine Disruptor Screening Program. Data Evaluation Records were used to collate the control variability...
Search relevance: 78.07 | Views last month: 0 -
Alternative complement pathway assay data observed in adult largemouth bass plasma in response to an EE2 (17alpha-ethinylestradiol) or mixture of estrone and atrazine exposure under laboratory...
Search relevance: 77.30 | Views last month: 0 -
Physiological endpoints observed in adult largemouth bass in response to an EE2 (17 alpha-ethinylestradiol) or mixture of estrone and atrazine exposure under laboratory pond conditions. Also...
Search relevance: 76.56 | Views last month: 0 -
The objective of this study was to develop a medium-throughput organotypic screening assay comprised of reconstructed human thyroid microtissues to quantitatively evaluate the disruptive effects...
Search relevance: 75.16 | Views last month: 1 -
Figures, tables, data for "Sara M F Vliet, Kristan J Markey, Scott G Lynn, Anna Adetona, Dawn Fallacara, Patricia Ceger, Neepa Choksi, Agnes L Karmaus, AtLee Watson, Andrew Ewans, Amber B Daniel,...
Search relevance: 74.60 | Views last month: 1 -
Dataset for "Combining in vitro and in silico New Approach Methods to investigate type 3 iodothyronine deiodinase chemical inhibition across species". This dataset is associated with the...
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This is a manuscript developed by a group at University of Berlin and Danish Technical University, using previously published data from EPA. The only EPA interaction has been providing advice on...
Search relevance: 74.43 | Views last month: 2 -
Structural defects in the rat brain associated with maternal exposure to ammonium perchlorate accompanied reductions in circulating levels of thyroid hormone in the dam and the fetus. The...
Search relevance: 73.77 | Views last month: 0 -
Dataset for Foley et al. 'Technical evaluation and standardization of the human thyroid microtissue assay'; Toxicological Sciences, Vol 199, Issue 1, pg 89-107, kfae014 May 2024. DOI...
Search relevance: 72.98 | Views last month: 0 -
Incedental wastewater reuse from streams that receive discharges from Wastewater Treatment Facilities (WWTF) has the potential to be a significant contributor of Endocrine Disrupting Chemicals. An...
Search relevance: 72.04 | Views last month: 0 -
A diverse data set of 1667 chemicals with AR experimental activity were provided by the U.S. EPA from the oxicity Forecaster (ToxCast) program which generates data using in vitro high-throughput...
Search relevance: 69.80 | Views last month: 0 -
The data presented include concentrations of 122 organic, 23 inorganic constituents, and estrogenicity in water collected from 13 off-stream non-point source sites (natural and created wetlands)...
Search relevance: 65.70 | Views last month: 0 -
This data release presents chemical and biological results from investigations of water quality, fish endocrine disruption, and emergent insects in the Shenandoah River Watershed (Virginia and...
Search relevance: 63.68 | Views last month: 0
