Found 20 datasets matching "glucocorticoid-receptor".
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Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding...
Search relevance: 230.08 | Views last month: 0 -
We have previously shown that neuroendocrine activation leading to increased circulating stress hormones was necessary for mediating ozone-induced lung injury and inflammation since adrenalectomy...
Search relevance: 217.51 | Views last month: 1 -
Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation
This data set contains one Excel file. In this file are all the data pertaining to the effects of propranolol and mifepristone on ozone induced lung injury and inflammation . The different tabs of...
Search relevance: 216.83 | Views last month: 1 -
Background In most cells glucocorticoid receptors (GR) reside predominately in the cytoplasm. Upon hormone binding, the GR translocates into the nucleus, where the hormone-activated...
Search relevance: 206.25 | Views last month: 0 -
Raw data for glucocorticoid receptor ligand exposure experiments. This dataset is associated with the following publication: MedlockKakaley, E., M. Cardon, E. Gray, P. Hartig, and V. Wilson....
Search relevance: 140.70 | Views last month: 0 -
Raw data for glucocorticoid receptor ligand exposure experiments. This dataset is associated with the following publication: MedlockKakaley, E., M. Cardon, E. Gray, P. Hartig, and V. Wilson....
Search relevance: 138.82 | Views last month: 1 -
Raw data for each glucocorticoid ligand mixtures experiment. This dataset is associated with the following publication: MedlockKakaley, E., M. Cardon, E. Gray, P. Hartig, and V. Wilson....
Search relevance: 131.83 | Views last month: 0 -
This data set pertains to the manuscript "Exacerbation of ozone-induced pulmonary and systemic effects by 2-adrenergic and/or glucocorticoid agonist/s". It shows the raw data for each figure in...
Search relevance: 74.66 | Views last month: 0 -
Dorsal third ventricle infusions of the alpha 2 adrenergic receptor antagonist, mianserin- which increases brain concentrations of dopamine, serotonin, and acetylcholine, or the glucocorticoid...
Search relevance: 73.28 | Views last month: 0 -
Although endocrine disrupting compounds have been detected in wastewater and surface waters worldwide using a variety of in vitro effects-based screening tools, e.g. bioassays, few have examined...
Search relevance: 71.08 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays...
Search relevance: 69.79 | Views last month: 0 -
It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular mechanisms. Glucocorticoids...
Search relevance: 60.66 | Views last month: 0 -
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene expression of...
Search relevance: 59.32 | Views last month: 0 -
A manuscript describing the independent roles of beta adrenergic and glucocorticoid receptors in mediating ozone-induced pulmonary and systemic effects. This dataset is associated with the...
Search relevance: 58.17 | Views last month: 0 -
Detected in vitro estrogen, androgen, and glucocorticoid receptor activity,in samples in the 2018 tapwater study in Cape Cod, Massachusetts. This dataset is associated with the following...
Search relevance: 58.03 | Views last month: 0 -
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene expression of...
Search relevance: 56.82 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a pilot study of US tapwaters. In vitro bioassays include T47D-Kbluc, MDA-kb2, and...
Search relevance: 52.47 | Views last month: 1 -
This dataset contains the concentration and quality assurance results for inorganic and organic analytes collected for the U.S. Geological Survey (USGS), Ecosystems Mission Area, Environmental...
Search relevance: 49.75 | Views last month: 0 -
The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
Search relevance: 49.38 | Views last month: 0 -
Background Members of the Rab GTPase family regulate intracellular protein trafficking, but the specific function of Rab24 remains unknown. Several attributes distinguish this protein...
Search relevance: 45.62 | Views last month: 0