Found 73 datasets matching "hepatic".
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Background: Hepatic injury after ischemia/reperfusion is attributed to the development of oxygen free radical (OFR)-mediated lipid peroxidation - a process that can be measured...
Search relevance: 130.69 | Views last month: 2 -
Background The hepatic stellate cell is the primary cell type responsible for the excessive formation and deposition of connective tissue elements during the development of hepatic...
Search relevance: 128.21 | Views last month: 2 -
Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis....
Search relevance: 127.26 | Views last month: 1 -
Air pollution has been associated with metabolic diseases and hepatic steatosis-like changes. We have shown that ozone alters liver gene expression for metabolic processes through neuroendocrine...
Search relevance: 124.83 | Views last month: 0 -
Dataset for "Crizer, D.M.; Rice, J.R.; Smeltz, M.G.; Lavrich, K.S.; Ravindra, K.; Wambaugh, J.F.; DeVito, M.; Wetmore, B.A. In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl...
Search relevance: 116.98 | Views last month: 1 -
Background Hepatic surgery is characterized by complicated operations with a significant peri- and postoperative risk for the patient. We developed a web-based, high-granular research...
Search relevance: 116.68 | Views last month: 0 -
Background Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in...
Search relevance: 114.53 | Views last month: 0 -
Background The role of glucokinase (GCK) in the pathogenesis of maturity-onset diabetes of the young is well established. However, its role in the common form of type 2 diabetes is far...
Search relevance: 112.37 | Views last month: 1 -
The data used in this manuscript came from published literature. This dataset is associated with the following publication: Bay, C., and H. El-Masri. A biologically based model to quantitatively...
Search relevance: 108.32 | Views last month: 0 -
Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly...
Search relevance: 104.80 | Views last month: 0 -
This dataset illustrates relationships between body weight and hepatic phase I and phase II metabolic activity in rainbow trout. This dataset is associated with the following...
Search relevance: 103.78 | Views last month: 1 -
Jaleh A. Abedini, Sakshi Handa, Stephen Edwards, Brian Chorley, Hisham El-Masri, Identification of differentially expressed genes and networks related to hepatic lipid dysfunction, Toxicology and...
Search relevance: 97.54 | Views last month: 0 -
The toxicity of liver and kidney upon acute and subacute exposure to bromochloromethane in both male and female rats. This dataset is associated with the following publication: Simmons, J., T....
Search relevance: 89.70 | Views last month: 1 -
Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the carbon chain. Next-generation...
Search relevance: 87.55 | Views last month: 2 -
Gene expression data from the Fluidigm qRT-PCR arrays was analyzed in R (v3.6.1; R Foundation for Statistical Computing, 2019). Prior to processing through the tcpl package, each qRT-PCR primer...
Search relevance: 86.57 | Views last month: 2 -
Dataset for Robarts et al., 'Hepatic Transcriptome Comparative In Silico Analysis Reveals Similar Pathways and Targets Altered by Legacy and Alternative Per- and Polyfluoroalkyl Substances in...
Search relevance: 86.27 | Views last month: 0 -
Dataset for "Kolanczyk, R.C.; Solem, L.E.; Schmieder, P.K.; McKim, J.M., III. A Comparative Study of Phase I and II Hepatic Microsomal Biotransformation of Phenol in Three Species of Salmonidae:...
Search relevance: 85.82 | Views last month: 0 -
This dataset, presented as an Excel spreadsheet, contains all data presented as figures and tables in an article by Nichols et al, entitled "In vitro-in vivo extrapolation of hepatic...
Search relevance: 83.61 | Views last month: 1 -
A number of brominated flame retardants (BFRs) have been reported to interfere with the thyroid signaling pathway and cause oxidative stress in birds, yet the underlying shifts in gene expression...
Search relevance: 77.56 | Views last month: 0 -
Data and supplemental figures for manuscript titled "Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs." We used a...
Search relevance: 65.07 | Views last month: 1