Found 38 datasets matching "homology".
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Background Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often share similar...
Search relevance: 91.75 | Views last month: 0 -
The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors....
Search relevance: 82.89 | Views last month: 0 -
A novel peptide sequence having the general formula AB wherein each of A and B represent a chain of amino acid residues and wherein said A chain is capable of binding with a mojor...
Search relevance: 44.87 | Views last month: 0 -
Background Inhibitor of Apoptosis (IAP) proteins are key intrinsic regulators of apoptosis induced by a variety of triggers. We isolated the rat Inhibitor of Apoptosis genes 1, 2 and 3...
Search relevance: 44.25 | Views last month: 0 -
Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Search relevance: 42.71 | Views last month: 0 -
Background Current evidence suggests that lepidopteran baculoviruses may be divided into two phylogenetic groups based on their envelope fusion proteins. One group utilizes gp64, a low...
Search relevance: 40.49 | Views last month: 0 -
Background The function of proteins is a direct consequence of their three-dimensional structure. The structural classification of proteins describes the ways of folding patterns all...
Search relevance: 39.57 | Views last month: 0 -
Data for "John K. Colbourne, Joseph R. Shaw, Elena Sostare, Claudia Rivetti, Romain Derelle, Rosemary Barnett, Bruno Campos, Carlie LaLone, Mark R. Viant, Geoff Hodges, Toxicity by descent: A...
Search relevance: 35.30 | Views last month: 0 -
Background The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src homology 3) domain....
Search relevance: 34.31 | Views last month: 0 -
Background: Cohesin is a macromolecular complex that links sister chromatids together at the metaphase plate during mitosis. The links are formed during DNA replication and destroyed...
Search relevance: 33.63 | Views last month: 0 -
Background The acetamidase of Mycobacterium smegmatis is a highly inducible enzyme. Expression of this enzyme is increased 100-fold when the substrate acetamide is present. The...
Search relevance: 33.07 | Views last month: 0 -
In the present study 55 IgVH genes amplified from three different anatomical regions of a rheumatoid arthritis (RA) patient were analyzed, adding further information on synovial B-cell...
Search relevance: 32.23 | Views last month: 0 -
Background The proteinase-activated receptor 4 (PAR4) is a G-protein-coupled receptor activated by proteases such as thrombin and trypsin. Although activation of PAR4 has been shown to...
Search relevance: 29.53 | Views last month: 0 -
Background Members of the p24 (p24/gp25L/emp24/Erp) family of proteins have been shown to be critical components of the coated vesicles that are involved in the transportation of cargo...
Search relevance: 28.76 | Views last month: 0 -
Background Echoviruses are the commonest cause of aseptic meningitis. Echovirus type 13 which has not been isolated in Germany over a long period of time was the predominant enterovirus...
Search relevance: 28.39 | Views last month: 1 -
Background: The formin family of proteins has been implicated in signaling pathways of cellular morphogenesis in both animals and fungi; in the latter case, at least, they participate in...
Search relevance: 28.39 | Views last month: 0 -
Background Scorpion venom contains insect and mammal selective toxins. We investigated the venom of the South Indian red scorpion, Mesobuthus tamulus for the purpose of identifying...
Search relevance: 28.03 | Views last month: 0 -
Background Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other aromatic-pathway...
Search relevance: 27.39 | Views last month: 0 -
Background The ubiquitin-dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitinating enzymes constitute a complex...
Search relevance: 26.78 | Views last month: 0 -
A binding molecule comprising a support structure of at least one cyclic molecular subunit and at least two side chain subunits, where the side chain subunits are polypeptide chains containing...
Search relevance: 26.67 | Views last month: 0
