Found 65 datasets matching "in vitro model".
-
Supplementary data for "H.A. Fisher, M.V. Evans, A.L. Bunge, E.A. Cohen Hubal, D.A. Vallero, A compartment model to predict in vitro finite dose absorption of chemicals by human skin, Chemosphere,...
Search relevance: 166.20 | Views last month: 0 -
Epithelial-mesenchymal interactions drive embryonic fusion events during development and upon perturbation can result in birth defects. Cleft palate and neural tube defects can result from genetic...
Search relevance: 113.19 | Views last month: 0 -
Microbiome analyses. This dataset is associated with the following publication: Griggs, J., L. Chi, N. Hanley, M. Kohan, K. Herbin-Davis, D. Thomas, K. Lu, R. Fry, and K. Bradham....
Search relevance: 111.26 | Views last month: 0 -
The objective of this study was to develop a medium-throughput organotypic screening assay comprised of reconstructed human thyroid microtissues to quantitatively evaluate the disruptive effects...
Search relevance: 110.15 | Views last month: 1 -
Dataset for manuscript titled, "Ozone responsive gene expression as a model for describing repeat exposure response trajectories and inter-individual toxicodynamic variability in vitro" published...
Search relevance: 109.26 | Views last month: 0 -
This dataset comprises one SigmaPlot 13 file containing measured survival data and survival data predicted from the model coefficients selected by the LASSO procedure. This dataset is associated...
Search relevance: 80.65 | Views last month: 0 -
This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the two chemicals tested,...
Search relevance: 76.20 | Views last month: 1 -
Using the SHIME (an in vitro simulator of the human gut microbiome) we tracked the fate of the probiotic Lacticaseibacillus rhamnosus GG (LGG) over time and across colonic regions. Using fecal...
Search relevance: 63.93 | Views last month: 0 -
This paper described development of an in vitro/in vivo model that accounts for first pass clearance effects. The model details are contained in the supporting information for the paper. This...
Search relevance: 54.82 | Views last month: 0 -
This file contains the analyzed dataset for each figure/table in the manuscript. This dataset is associated with the following publication: Lehmann , D., and W. Williams. Development and...
Search relevance: 51.90 | Views last month: 0 -
A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
Search relevance: 51.54 | Views last month: 0 -
Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
Search relevance: 50.17 | Views last month: 0 -
1) % Viability of human reconstructed skin exposed to cerium, silver and titanium nanoparticles; 2) Zeta potential of the nanoparticles in media. This dataset is associated with the following...
Search relevance: 49.78 | Views last month: 1 -
Data sets in the context of this project are the model files, model input parameter sets, and data generated at the US EPA/ORD/National Health and Environmental Effects Research Laboratory that...
Search relevance: 48.86 | Views last month: 0 -
The purpose of is this study was to evaluate the potential for biotransformation in the gastrointestinal tissues (GIT) of fish to impact chemical bioaccumulation. In vitro biotransformation of...
Search relevance: 48.53 | Views last month: 0 -
The data released are associated with an examination of eDNA from round goby fish (Neogobius melanostomus) in a series of field sample collections (lake nearshore and stream transport) and in...
Search relevance: 46.15 | Views last month: 0 -
Datasets for Benjamin Deacon, et al. 'Computational Modelling of the Impact of Evaporation on In-Vitro Dermal Absorption', Pharmaceutical Research, Vol 41, pg 1979-1990, 2024, DOI...
Search relevance: 45.65 | Views last month: 0 -
Organogenesis in the embryo involves cell differentiation and organization events that are unique to each tissue and organ and are susceptible to developmental toxicants. Animal models are the...
Search relevance: 45.55 | Views last month: 1 -
Screening certain environmental chemicals for their ability to interact with endocrine targets, including the androgen receptor (AR), is an important global concern. We previously developed a...
Search relevance: 45.23 | Views last month: 0 -
The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
Search relevance: 44.29 | Views last month: 0
