Found 61 datasets matching "inflammatory-response".
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This dataset contains a summary of compounds found in human blood samples. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living...
Search relevance: 128.94 | Views last month: 0 -
Recent work has established that IL-1β plays a central role in the inflammation and connective tissue destruction observed in both rheumatoid arthritis and osteoarthritis. These processes result...
Search relevance: 118.68 | Views last month: 0 -
An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs. Resources in this dataset: Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and...
Search relevance: 114.90 | Views last month: 0 -
The cytokine tumour necrosis factor (TNF)α is a vital mediator of the innate immune response, and a pleiotropic regulator of cellular function. Its involvement in rheumatoid arthritis is...
Search relevance: 102.03 | Views last month: 0 -
The production of superantigenic exotoxins by Gram positive bacteria underlies the pathology of toxic shock syndrome. Future treatment strategies for superantigen-mediated diseases are likely to...
Search relevance: 94.11 | Views last month: 0 -
Various stressors including temperature, environmental chemicals and toxins can have profound impacts on immunity to pathogens. It is believed that increased eutrophication near rivers and lakes...
Search relevance: 85.69 | Views last month: 0 -
Background Experimental colitis with features similar to inflammatory bowel disease (IBD) has initially been described. A detailed analysis of inflammatory cells has not yet been...
Search relevance: 63.42 | Views last month: 0 -
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed in the treatment of...
Search relevance: 60.73 | Views last month: 5 -
Compositions for reducing an adverse skin reaction caused by a skin-irritating agent or skin sensitizing agent by treatment with a disaccharide and a metal ion, as well as methods for reducing an...
Search relevance: 60.42 | Views last month: 1 -
We tested the postulate that 1) a fulvic acid (FA)-like substance is included in cigarette smoke and wood smoke particles and 2) exposure of respiratory epithelial cells to this substance results...
Search relevance: 58.80 | Views last month: 0 -
Background Invasion and metastasis is a complex process governed by the interaction of genetically altered tumor cells and the immunological and inflammatory host reponse. Specific...
Search relevance: 57.04 | Views last month: 0 -
The present invention relates to topical oral care compositions comprising in a pharmaceutically acceptable carrier a safe and effective amount of a host-response modulating agent including one or...
Search relevance: 52.38 | Views last month: 0 -
Interleukin-1 receptor antagonist (IL-1Ra) is a natural IL-1 inhibitor possessing anti-inflammatory properties. IL-1Ra is produced as different isoforms, one secreted (sIL-1Ra) and three...
Search relevance: 52.32 | Views last month: 0 -
In this issue of the journal, Steinwaldet al[1] extend limited clinical studies and report an animal experiment showing that calcitonin precursors (predominantly procal-citonin) are...
Search relevance: 51.31 | Views last month: 0 -
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in acute lung injury...
Search relevance: 50.51 | Views last month: 0 -
Severe sepsis continues to lead to critical illness. Few therapeutic options exist other than antibiotic therapy and general supportive care. Large numbers of patients continue to die as a...
Search relevance: 49.79 | Views last month: 1 -
This dataset provides information on the season of particle collection, the polarization state of a given macrophage, the impacts on macrophage functions. This dataset is associated with the...
Search relevance: 49.65 | Views last month: 0 -
The autoantigenic polymyositis/scleroderma (PM/Scl) complex was recently shown to be the human homologue of the yeast exosome, which is an RNA-processing complex. Our aim was to assess whether, in...
Search relevance: 49.34 | Views last month: 0 -
Human tumour necrosis factor (TNF)-like weak inducer of apoptosis (hTWEAK) and two anti-hTWEAK mAbs were tested for their ability to elicit or block inflammatory responses in cultured human dermal...
Search relevance: 49.19 | Views last month: 1 -
Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the prevalent etiology of heart...
Search relevance: 48.75 | Views last month: 2
