Found 161 datasets matching "mRNA".
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Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket. However, the...
Search relevance: 131.92 | Views last month: 0 -
Background We describe an alternative method to determine mRNA half-life (t1/2) based on the Real-Time RT-PCR procedure. This approach was evaluated by using the β-actin gene as a...
Search relevance: 128.12 | Views last month: 0 -
Background Previous studies by Volloch and coworkers have reported that during the expression of high levels of β-globin mRNA in the spleen of anemic mice, they could also detect small...
Search relevance: 121.92 | Views last month: 0 -
Background Vascular endothelial growth factor (VEGF) mRNA levels increase in rat skeletal muscle after a single bout of acute exercise. We assessed regional differences in VEGF165 mRNA...
Search relevance: 118.88 | Views last month: 0 -
Background Human herpesvirus-8 (HHV-8) is linked to the pathogenesis of Kaposi's sarcoma (KS), and the HHV-8 DNA load in peripheral blood mononuclear cells (PBMC) is associated with the...
Search relevance: 117.58 | Views last month: 0 -
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to limited accessibility...
Search relevance: 98.96 | Views last month: 1 -
Constitutive mRNA expression and secretion of proinflammatory and anti-inflammatory cytokines was comparatively analyzed in rheumatoid arthritis (RA) synovial fibroblasts (SFB), isolated from...
Search relevance: 86.03 | Views last month: 0 -
Background Soluble guanylyl cyclase (sGC) is the main receptor for nitric oxide (NO) when the latter is produced at low concentrations. This enzyme exists mainly as a heterodimer...
Search relevance: 84.66 | Views last month: 0 -
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model system for gallbladder...
Search relevance: 84.15 | Views last month: 0 -
Data for "Estrogenic Activity of Perfluoro Carboxylic and Sulfonic Acids in Rainbow Trout Estrogen Receptor Binding and Liver Slice Vtg mRNA Expression Assays. Mark A. Tapper, Jeffrey S. Denny,...
Search relevance: 79.07 | Views last month: 0 -
data was from HepG2 cells treated with nano-silver particles using silver nitrate as negative controls. Differentially expressed messenger RNA and microRNA were obtained by RNA sequencing and...
Search relevance: 78.48 | Views last month: 0 -
DLD-1 and MOLT-4 cell lines were cultured in a Rotating cell culture system to simulate microgravity and mRNA expression profile was observed in comparison to Static controls. Cells were grown in...
Search relevance: 76.38 | Views last month: 0 -
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls. Cells were grown in 10mL rotating...
Search relevance: 73.12 | Views last month: 0 -
The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors....
Search relevance: 63.13 | Views last month: 0 -
Relative mRNA levels from maize organs have been quantified by hybridization to maize arrays fabricated with 5,376 unique expressed sequence tag clones. mRNAs from embryos, three vegetative organs...
Search relevance: 62.93 | Views last month: 0 -
Air pollution has been associated with metabolic diseases and hepatic steatosis-like changes. We have shown that ozone alters liver gene expression for metabolic processes through neuroendocrine...
Search relevance: 61.03 | Views last month: 0 -
This excel file contains the resultant data from a study on iodotyrosine deiodinase in the model amphibian species, Xenopus laevis. These data include: tadpole growth and development, thyroid...
Search relevance: 56.50 | Views last month: 0 -
Background The yeast yCCR4 factor belongs to the CCR4-NOT transcriptional regulatory complex, in which it interacts, through its leucine-rich repeat (LRR) motif with yPOP2. Recently,...
Search relevance: 55.34 | Views last month: 0 -
Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important...
Search relevance: 54.94 | Views last month: 0 -
The PESTO experiment was launched on April 8, 2002 onboard STS-110 (Atlantis) and was returned on June 19, 2002 onboard STS-111 (Endeavor), a total of 73 days in space. The ground control was...
Search relevance: 53.03 | Views last month: 0
