Found 20 datasets matching "mediator".
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Introduction: Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions among demographics, physiologic...
Search relevance: 72.09 | Views last month: 1 -
Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent oxidative stress. Although NO• is...
Search relevance: 63.72 | Views last month: 1 -
Figure 1. Comparison of cell viability in response to exposure of cells to oleic acid (in ethanol), a hydroxy-metabolite, or methylated oleic acid as percent of the vehicle control response....
Search relevance: 42.03 | Views last month: 1 -
The purpose of the study was to provide empirical data to inform the debate and lead to meaningful answers to questions in custody mediation and domestic violence including equity of outcomes for...
Search relevance: 40.99 | Views last month: 0 -
Background The regulation of programmed cell death is critical to developmental homeostasis and normal morphogenesis of embryonic tissues. Survivin, a member of the inhibitors of...
Search relevance: 39.09 | Views last month: 0 -
Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and...
Search relevance: 38.93 | Views last month: 0 -
The cytokine tumour necrosis factor (TNF)α is a vital mediator of the innate immune response, and a pleiotropic regulator of cellular function. Its involvement in rheumatoid arthritis is...
Search relevance: 36.89 | Views last month: 0 -
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed in the treatment of...
Search relevance: 36.49 | Views last month: 5 -
Topically applicable agents are described, for the treatment of nail diseases and for nail care, which contain where needed, besides one or more active substance and physiologically compatible...
Search relevance: 36.30 | Views last month: 1 -
In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of granuloma formation and since...
Search relevance: 36.30 | Views last month: 0 -
Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2) cytokine gene cluster on...
Search relevance: 35.17 | Views last month: 1 -
Records documenting routine activities related to programs such as reasonable accommodation, displaced employees, telework/alternative worksite opportunities, anti-harassment, Alternative Dispute...
Search relevance: 35.17 | Views last month: 0 -
The Texas Department of Insurance administers Independent Dispute Resolution (IDR), a mediation and arbitration process for certain health care billing disputes between out-of-network providers...
Search relevance: 32.16 | Views last month: 2 -
Background The greater susceptibility of children to renal injury in post-diarrheal hemolytic-uremic syndrome (HUS) may be related, at least in part, to heightened renal cell sensitivity...
Search relevance: 30.06 | Views last month: 0 -
Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are considered to be master cytokines in chronic, destructive arthritis. Therapeutic approaches in rheumatoid arthritis (RA) patients have so...
Search relevance: 29.83 | Views last month: 1 -
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in acute lung injury...
Search relevance: 29.63 | Views last month: 0 -
Background Ethylene is a widely distributed alkene product which is formed enzymatically (e.g., in plants) or by photochemical reactions (e.g., in the upper oceanic layers from dissolved...
Search relevance: 29.33 | Views last month: 0 -
These data are part of NACJD's Fast Track Release and are distributed as they were received from the data depositor. The files have been zipped by NACJD for release, but not checked or processed...
Search relevance: 27.14 | Views last month: 0 -
Background Endothelium dysfunction is believed to play a role in the development of cardiovascular disease. The aim of the present study was to evaluate the suitability of organ culture...
Search relevance: 25.56 | Views last month: 0 -
Perfluorononanoic acid (PFNA) is one of the perfluoroalkyl acids found in the environment and in tissues of humans and wildlife. Prenatal exposure to PFNA negatively impacts survival and...
Search relevance: 23.19 | Views last month: 0
