Found 16 datasets matching "murine-model".
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A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent antibodies to glucose-6-phosphate...
Search relevance: 105.59 | Views last month: 0 -
Background Cystinosis is an autosomal recessive disorder characterised by an intralysosomal accumulation of cystine, and affected individuals progress to end-stage renal failure before...
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To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-mIL-4) was used for...
Search relevance: 48.98 | Views last month: 0 -
Staphylococcus aureus is one of the most important pathogens in septic arthritis. To analyse the arthritogenic properties of staphylococcal peptidoglycan (PGN), highly purified PGN from S. aureus...
Search relevance: 47.25 | Views last month: 0 -
Background Monolysocardiolipin acyltransferase (MLCL AT) catalyzes the acylation of monolysocardiolipin to cardiolipin in mammalian tissues. We previously reported that cardiac...
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The interaction of particulates with resident macrophages is a consistent feature in certain forms of crystal-induced inflammation, for example, in synovial tissues, lung, and the peritoneum. The...
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Because angiogenesis plays a major role in the perpetuation of inflammatory arthritis, we explored a method for selectively targeting and destroying new synovial blood vessels. Mice with...
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Background Gene transfer studies in primary T cells have suffered from the limitations of conventional viral transduction or transfection techniques. Replication-defective adenoviral...
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Background CMV infections have been linked to vasculopathies like atherosclerosis and Scleroderma. CMV infects vascular endothelium with intermittent shedding of the virus and the...
Search relevance: 30.76 | Views last month: 0 -
Dedication This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine,...
Search relevance: 28.71 | Views last month: 1 -
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen, Candida albicans, grown in spaceflight conditions....
Search relevance: 25.41 | Views last month: 0 -
https://c3.nasa.gov/genelab/accession/GLDS-20/ This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen,...
Search relevance: 24.28 | Views last month: 0 -
https://c3.nasa.gov/genelab/accession/GLDS-20/ This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen,...
Search relevance: 23.67 | Views last month: 3 -
https://c3.nasa.gov/genelab/accession/GLDS-20/ This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen,...
Search relevance: 23.67 | Views last month: 0 -
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene...
Search relevance: 22.37 | Views last month: 0 -
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene...
Search relevance: 22.37 | Views last month: 0
