Found 26 datasets matching "pro-inflammatory".
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The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease
The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to the destruction of normal...
Search relevance: 247.30 | Views last month: 1 -
The cytokine tumour necrosis factor (TNF)α is a vital mediator of the innate immune response, and a pleiotropic regulator of cellular function. Its involvement in rheumatoid arthritis is...
Search relevance: 226.01 | Views last month: 0 -
Background Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce...
Search relevance: 179.72 | Views last month: 0 -
We tested the postulate that 1) a fulvic acid (FA)-like substance is included in cigarette smoke and wood smoke particles and 2) exposure of respiratory epithelial cells to this substance results...
Search relevance: 150.93 | Views last month: 0 -
Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent oxidative stress. Although NO• is...
Search relevance: 111.73 | Views last month: 1 -
Excel files for "A fulvic acid-like substance participates in the pro-inflammatory effects of cigarette smoke and wood smoke particles". This dataset is not publicly accessible because: Not...
Search relevance: 59.96 | Views last month: 0 -
Chronic airway inflammation is one of the main features of asthma. Release of mediators from infiltrating inflammatory cells in the airway mucosa has been proposed to contribute directly or...
Search relevance: 59.56 | Views last month: 0 -
The program at this year's American Thoracic Society international conference included over 300 scientific and clinical symposia. In this report I have reviewed the data presented on two important...
Search relevance: 58.92 | Views last month: 0 -
Cell investigation into mechanism of particle-related biological effect. This dataset is associated with the following publication: Ghio, A., J. Soukup, J. Stonehuerner , H. Tong, J. Richards,...
Search relevance: 56.24 | Views last month: 0 -
Data include assessment of pro-inflammatory cytokines, epithelial integrity, bulk RNA sequencing, and gene expression changes in human airway epithelial cells exposed to burn pit smoke...
Search relevance: 52.61 | Views last month: 0 -
The abundance and activation of macrophages in the inflamed synovial membrane/pannus significantly correlates with the severity of rheumatoid arthritis (RA). Although unlikely to be the...
Search relevance: 52.60 | Views last month: 0 -
Data include assessment of transepithelial electrical resistance, lactate dehydrogenase, toxicity scores, pro-inflammatory cytokines, and modulation of gene expression in human airway epithelial...
Search relevance: 50.97 | Views last month: 0 -
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding...
Search relevance: 50.95 | Views last month: 0 -
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to determine the levels of...
Search relevance: 48.97 | Views last month: 0 -
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to determine the levels of...
Search relevance: 48.97 | Views last month: 0 -
The intricate interactions that regulate relationships between endogenous tissue cells and infiltrating immune cells in the rheumatic joint, particularly in rheumatoid arthritis (RA), were the...
Search relevance: 48.57 | Views last month: 0 -
Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of...
Search relevance: 48.09 | Views last month: 0 -
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to determine the levels of...
Search relevance: 46.70 | Views last month: 0 -
These data are summaries of pro-inflammatory cytokine and insulin resistance serum biomarkers; necrotic liver disease defined by serum keratin 18 (K18) biomarkers. Associations were determined...
Search relevance: 45.70 | Views last month: 0
