Found 71 datasets matching "protein-domain".
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Background Members of the p24 (p24/gp25L/emp24/Erp) family of proteins have been shown to be critical components of the coated vesicles that are involved in the transportation of cargo...
Search relevance: 149.37 | Views last month: 0 -
Using computational sequence-profile analysis methods, a previously uncharacterized, predicted α-helical domain of about 85 residues was identified in chromosomal proteins such as Swi3p, Rsc8p,...
Search relevance: 116.62 | Views last month: 0 -
Background The cyclic AMP specific phosphodiesterase, PDE4D5 interacts with the β-propeller protein RACK1 to form a signaling scaffold complex in cells. Two-hybrid analysis of truncation...
Search relevance: 112.16 | Views last month: 0 -
Background The membrane-bound cell-surface precursor and soluble forms of heparin-binding epidermal growth factor-like growth factor (HB-EGF) contribute to many cellular developmental...
Search relevance: 111.46 | Views last month: 0 -
Iron uptake from the host is essential for bacteria that infect animals. A protein domain has been identified that appears in variable copy number in bacterial genes that are usually in the...
Search relevance: 109.17 | Views last month: 0 -
The dataset has all of the information used to create and evaluate 3 independent QSAR models for the fraction of a chemical unbound by plasma protein (Fub) for environmentally relevant chemicals....
Search relevance: 96.32 | Views last month: 20 -
Background The function of proteins is a direct consequence of their three-dimensional structure. The structural classification of proteins describes the ways of folding patterns all...
Search relevance: 92.60 | Views last month: 0 -
Background The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src homology 3) domain....
Search relevance: 83.23 | Views last month: 0 -
Transformed cells obtained by transferring into normal cells with a gene encoding a protein capable of phosphorylation of p38 protein, or the p38 protein, a variant of the p38 protein, the kinase...
Search relevance: 66.00 | Views last month: 0 -
Background Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. Bloom syndrome cells...
Search relevance: 62.90 | Views last month: 0 -
Background Norwalk virus causes outbreaks of acute non-bacterial gastroenteritis in humans. The virus capsid is composed of a single 60 kDa protein. In a previous study, the capsid...
Search relevance: 61.22 | Views last month: 0 -
The PRC-H β-barrel domain, a distinct cytoplasmic β-barrel domain whose fold has no close structural relationship to any other well known β-barrel domain, is the prototype of a novel superfamily...
Search relevance: 60.61 | Views last month: 0 -
Constraint-Based Multiple Alignment Tool (COBALT) is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein...
Search relevance: 59.95 | Views last month: 0 -
Identifies the conserved domains present in a protein sequence. CD-Search uses RPS-BLAST (Reverse Position-Specific BLAST) to compare a query sequence against position-specific score matrices that...
Search relevance: 59.14 | Views last month: 0 -
The adaptor protein p130Cas(Cas) has been shown to be involved in different cellular processes including cell adhesion, migration and transformation. This protein has a substrate domain with up to...
Search relevance: 58.06 | Views last month: 0 -
Conserved Domain Database (CDD) is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins.
Search relevance: 57.69 | Views last month: 0 -
A new way to rapidly create functional, fluorescent fusion proteins: random insertion of GFP with an
Background The jellyfish green fluorescent protein (GFP) can be inserted into the middle of another protein to produce a functional, fluorescent fusion protein. Finding permissive sites...
Search relevance: 56.82 | Views last month: 1 -
Background: Differences in responses to bacterial surface lipopolysaccharides (LPSs) are apparent between and within mammalian species. It has been shown in mice that resistance to LPS...
Search relevance: 56.66 | Views last month: 0 -
The invention relates to the identification of a new protein that binds to the cytoplasmic domain of syndecan. This new protein, denominated as "syntenin", contains 298 amino acids and is...
Search relevance: 56.29 | Views last month: 0 -
Background The centromere is a specialized locus that mediates chromosome movement during mitosis and meiosis. This chromosomal domain comprises a uniquely packaged form of...
Search relevance: 56.26 | Views last month: 0
