Found 22 datasets matching "toxicological response".
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Several tables in documents and spreadsheets describing the toxicological dose response at the project sites. These files are provided as delivered.
Search relevance: 104.61 | Views last month: 0 -
Dataset for manuscript titled, "Ozone responsive gene expression as a model for describing repeat exposure response trajectories and inter-individual toxicodynamic variability in vitro" published...
Search relevance: 58.21 | Views last month: 0 -
This ScienceHub file shows the physiological data associated with the manuscript Adrenal Stress Hormone Regulation of Hepatic Homeostatic Function After an Acute Ozone Exposure in Wistar-Kyoto...
Search relevance: 57.43 | Views last month: 0 -
Dataset for Harrill, J.A. et al., 'Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping' published in Toxicological Sciences,...
Search relevance: 52.60 | Views last month: 0 -
This dataset contains 60-min locomotor response data for all control, chemical and particulate-extract-treated zebrafish. This dataset is associated with the following publication: Stevens, J.,...
Search relevance: 49.56 | Views last month: 0 -
This data set is broken up into 2 Excel files. In one file are all the data pertaining to the vascular and pulmonary effects of ozone exposure in rats fed either a normal diet or diet enriched...
Search relevance: 48.19 | Views last month: 1 -
This data set is an Excel file pertaining to the study that examined nasal, pulmonary, and systemic effects of acrolein in rats acutely exposed to a range of concentrations. The different tabs of...
Search relevance: 48.04 | Views last month: 0 -
Proportional response addition (Prop-RA), a model for predicting response from chemical mixture exposure, is demonstrated, and evaluated by statistically evaluating data on all possible binary...
Search relevance: 46.30 | Views last month: 1 -
This excel spreadsheet contains the resultant data for over from inhibition assays with human Deiodinase 1 screened against the ToxCast Phase 1 chemical library and a few additional chemicals. ...
Search relevance: 44.57 | Views last month: 2 -
We screened 44 chemicals in MCF7 cells in concentration response and generated HTTr data using the TempO-Seq hWTv1 assay. First, we provide an outline of the quality of the HTTr data based on a...
Search relevance: 44.10 | Views last month: 0 -
This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the two chemicals tested,...
Search relevance: 42.74 | Views last month: 1 -
These excel spreadsheets contains the resultant data from inhibition assays with human Iodothyronine Deiodinase Types 1, 2, and 3 screened against the ToxCast Phase 1_v2, Phase 2, and e1k chemical...
Search relevance: 42.40 | Views last month: 0 -
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human...
Search relevance: 37.76 | Views last month: 0 -
Whole transcriptomics dose response data is collected and storedthrough public facing Gene Expression Omnibus database. Raw collected viability/cytotoxicity data for each chemical are collected...
Search relevance: 37.48 | Views last month: 0 -
The fathead minnow (Pimephales promelas) is a key model of vertebrate toxicity. Standardized tests of toxicity in fathead minnow have been developed to support regulatory science, and much is...
Search relevance: 37.48 | Views last month: 0 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 37.43 | Views last month: 0 -
This study examined the biological response of aquatic organisms, collected in situ and from laboratory toxicity testing of water and soil to the herbicide Arsenal® primarily used to decrease the...
Search relevance: 33.61 | Views last month: 0 -
se of archival resources has been limited to date by inconsistent methods for genomic profiling of degraded RNA from formalin-fixed paraffin-embedded (FFPE) samples. RNA-seq offers a novel way to...
Search relevance: 33.46 | Views last month: 1 -
We used the Drosophila Genetics Reference Panel (DGRP), a collection of ~200 homozygous lines of fruit flies whose genomes have been sequenced. We quantified toluene-induced suppression of motor...
Search relevance: 31.61 | Views last month: 0 -
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that can generate...
Search relevance: 31.51 | Views last month: 0
