Found 23 datasets matching filters.
-
Data for "Kolanczyk RC, Saley MR, Serrano JA, Daley SM, Tapper MA. PFAS Biotransformation Pathways: A Species Comparison Study. Toxics. 2023 Jan 12;11(1):74. doi: 10.3390/toxics11010074. PMID:...
Search relevance: 1.00 | Views last month: 8 | Published on: 2025-08-02 -
Supporting information in "Saunders, L.J. and Nichols, J.W. (2023), Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
Data set to support the manuscript "Increased endocrine activity of xenobiotic chemicals as mediated by metabolic activation". Contains analytical measurement of metabolites, binding potential to...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Dataset for "Crizer, D.M.; Rice, J.R.; Smeltz, M.G.; Lavrich, K.S.; Ravindra, K.; Wambaugh, J.F.; DeVito, M.; Wetmore, B.A. In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
NTA output of 6:2 FTS microbial cultures Chu TAMU. This dataset is associated with the following publication: Yang, S., Y. Shi, M. Strynar, and K. Chu. Desulfonation and defluorination of 6:2...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This dataset, presented as an Excel spreadsheet, contains all data presented as figures and tables in an article by Nichols et al, entitled "In vitro-in vivo extrapolation of hepatic...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Supplementary material for "Kreutz, A.; Clifton, M.S.; Henderson, W.M.; Smeltz, M.G.; Phillips, M.; Wambaugh, J.F.; Wetmore, B.A. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This paper describes the results of an international ring trial (round robin study) of in vitro methods used to measure chemical biotransformation in fish. Researchers at six laboratories in the...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This dataset illustrates relationships between body weight and hepatic phase I and phase II metabolic activity in rainbow trout. This dataset is associated with the following...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
This paper described development of an in vitro/in vivo model that accounts for first pass clearance effects. The model details are contained in the supporting information for the paper. This...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
This dataset provides measured in vitro intrinsic clearance rates for 54 chemicals tested using isolated hepatocytes from humans, rats, and rainbow trout. The test chemicals were selected to...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Dataset for "Kolanczyk, R.C.; Solem, L.E.; Tapper, M.A.; Hoffman, A.D.; Sheedy, B.R.; Schmieder, P.K.; McKim, J.M., III. Sex-Linked Changes in Biotransformation of Phenol in Brook Trout...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
The dataset, which is presented as an Excel spreadsheet, contains all data which is presented as figures in Nichols et al., Measurement of kinetic parameters for biotransformation of polycyclic...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
This ScienceHub dataset provides characterization data for a pooled sample of trout liver S9 fractions that was used to study the in vitro intrinsic clearance of selected cationic surfactants. ...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
The purpose of is this study was to evaluate the potential for biotransformation in the gastrointestinal tissues (GIT) of fish to impact chemical bioaccumulation. In vitro biotransformation of...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
High-resolution mass spectrometry is advantageous for monitoring physiological impacts and contaminant biotransformation products in fish exposed to complex wastewater effluent. We evaluated this...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Organic ultraviolet filters (UVFs; also known as sunscreen agents) used in personal care and consumer products can enter the aquatic environment via wastewater treatment plant effluents or by loss...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
The purpose of this study was to compare two in vitro systems, cryopreserved trout hepatocytes and trout liver S9 fractions, used to predict in vivo levels of biotransformation in fish. This...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02
