Found 58 datasets matching "Screening assay".
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Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology...
Search relevance: 209.41 | Views last month: 0 -
The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the ToxCast Phase 1_v2, Phase 2, and...
Search relevance: 178.63 | Views last month: 0 -
This is an original dataset generated at the U.S. EPA. Data was analyzed with the ToxCast Pipeline and deposited for release in invitroDB accessible via the U.S. EPA CompTox Chemicals...
Search relevance: 150.97 | Views last month: 2 -
Dataset for Sakamuru, S., Ma, D., Pierro, J. D., Baker, N. C., Kleinstreuer, N., Cali, J. J., Knudsen, T. B., & Xia, M. (2024). Development and validation of CYP26A1 inhibition assay for...
Search relevance: 149.38 | Views last month: 0 -
Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol...
Search relevance: 143.71 | Views last month: 0 -
Dataset for article ‘Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening’ published 02/16/2022...
Search relevance: 139.65 | Views last month: 0 -
This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the two chemicals tested,...
Search relevance: 133.45 | Views last month: 1 -
Background The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. It has also been suggested for screening pharmacological activities in...
Search relevance: 104.17 | Views last month: 1 -
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body, facilitating predictions between...
Search relevance: 101.73 | Views last month: 2 -
Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake. This dataset is associated with the following...
Search relevance: 98.37 | Views last month: 1 -
This dataset contains all data and R code, in RMarkdown notebook format, needed to reproduce all statistical analysis, figures, and tables in the manuscript:Jeffers, D., J. S. Smith, E. D. Womack,...
Search relevance: 92.11 | Views last month: 2 -
These excel spreadsheets contains the resultant data from inhibition assays with human Iodothyronine Deiodinase Types 1, 2, and 3 screened against the ToxCast Phase 1_v2, Phase 2, and e1k chemical...
Search relevance: 90.15 | Views last month: 0 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 71.48 | Views last month: 0 -
In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
Search relevance: 64.56 | Views last month: 1 -
Dataset for S. Sakamuru, et al., 'Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes' published in Int'l Journal of Molecular Sciences, DOI...
Search relevance: 63.36 | Views last month: 0 -
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput...
Search relevance: 59.57 | Views last month: 0 -
This data set is comprised of three tables with results of algal toxin screening for saxitoxin and domoic acid. We used enzyme-linked immunosorbent assay (ELISA) and high-performance liquid...
Search relevance: 59.16 | Views last month: 0 -
Coastal communities are uniquely vulnerable to sea-level rise (SLR) and severe storms such as hurricanes. These events enhance the dispersion and concentration of natural and anthropogenic...
Search relevance: 58.55 | Views last month: 0 -
This data set is comprised of two tables with results of algal toxin screening for saxitoxin and domoic acid. We used enzyme-linked immunosorbent assay (ELISA) and high-performance liquid...
Search relevance: 57.82 | Views last month: 0 -
This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression...
Search relevance: 57.69 | Views last month: 0
