Found 100 datasets matching "ToxCast".
-
Supplemental files to accompany the manuscript: Feshuk et al., "The ToxCast Pipeline: Updates to Curve-fitting Approaches and Database Structure", DOI https://doi.org/10.3389/ftox.2023.1275980,...
Search relevance: 129.21 | Views last month: 0 -
These are the raw data files for TOXSCI manuscript 19-0578 entitled, “Respirometric Screening and Characterization of Mitochondrial Toxicants Within the ToxCast Phase I and II Chemical...
Search relevance: 126.16 | Views last month: 0 -
The tcpl package provides a set of tools for processing and modeling high-throughput and high-content chemical screening data. This dataset is associated with the following publication: Filer,...
Search relevance: 125.55 | Views last month: 0 -
The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
Search relevance: 124.15 | Views last month: 0 -
ToxCast is used as a cost-effective approach for efficiently prioritizing the toxicity testing of thousands of chemicals. It uses data from state-of-the-art high throughput screening (HTS)...
Search relevance: 123.46 | Views last month: 1 -
A data set of 500 chemicals evaluated for their ability to induce cleft palate in animal prenatal developmental studies was compiled from Toxicity Reference Database and the biomedical literature,...
Search relevance: 120.74 | Views last month: 1 -
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the food-relevant chemical universe...
Search relevance: 119.32 | Views last month: 2 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 117.86 | Views last month: 6 -
Excel file containing ToxCast bioactivity data for carbaryl, celecoxib, chromium triacetate, HgCl2, nonylphenol, pentachlorophenol, PFOA, PFOS, pioglitazone, sodium dichromate, TCDD. The .zip...
Search relevance: 106.98 | Views last month: 0 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 104.94 | Views last month: 0 -
This file contains the data used to generate hit calls from neural activity recordings on microelectrode array (MEA) plates treated with ToxCast compounds at a single concentration. This dataset...
Search relevance: 102.65 | Views last month: 1 -
Bioactivity data for p,p'-DDD and analogues from ToxCast assays conducted in liver cells were sourced from the EPA’s CompTox Chemistry Dashboard. The links also provide access to the ToxCast assay...
Search relevance: 100.63 | Views last month: 0 -
Background: High-content imaging (HCI) allows simultaneous measurement of multiple cellular phenotypic changes and is an important tool for evaluating the biological activity of...
Search relevance: 94.31 | Views last month: 0 -
Supplemental datafiles for journal article 'High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells'.
Search relevance: 93.40 | Views last month: 0 -
This excel spreadsheet contains the resultant data for over from inhibition assays with human Deiodinase 1 screened against the ToxCast Phase 1 chemical library and a few additional chemicals. ...
Search relevance: 93.36 | Views last month: 2 -
Supplemental data for "Schaupp CM, Maloney EM, Mattingly K, Olker JH, Villeneuve DL. Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a role for ToxCast data in...
Search relevance: 87.57 | Views last month: 1 -
ToxCast bioactivity data and model predictions for the ER and AR pathways for p,p'-DDD and analogues
ToxCast bioactivity data and model predictions for the estrogen receptor (ER) and androgen receptor (AR) pathways were obtained from the inks provided. This dataset is associated with the...
Search relevance: 84.45 | Views last month: 1 -
Abbreviations and data for manuscript Figures in the main text and supplemental. This dataset is associated with the following publication: Stoker, T., J. Want, A. Murr, J. Bailey, and A.R....
Search relevance: 83.06 | Views last month: 1 -
These excel spreadsheets contains the resultant data from inhibition assays with human Iodothyronine Deiodinase Types 1, 2, and 3 screened against the ToxCast Phase 1_v2, Phase 2, and e1k chemical...
Search relevance: 82.49 | Views last month: 0 -
The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the ToxCast Phase 1_v2, Phase 2, and...
Search relevance: 80.59 | Views last month: 0
