Found 8 datasets matching "asthma-susceptibility".
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Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2) cytokine gene cluster on...
Search relevance: 226.00 | Views last month: 1 -
Asthma is the most common chronic childhood disease in the developed nations, and is a complex disease that has high social and economic costs. Studies of the genetic etiology of asthma offer a...
Search relevance: 123.32 | Views last month: 0 -
Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major achievements have occurred in...
Search relevance: 74.05 | Views last month: 3 -
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to...
Search relevance: 73.05 | Views last month: 0 -
The present invention describes a susceptibility locus which is functionally related to asthma. The locus maps within human chromosome 7p15-p14. The invention also describes a novel human gene,...
Search relevance: 69.04 | Views last month: 0 -
Asthma is a complex heritable inflammatory disorder of the airways in which the development of clinical disease depends on environmental exposure. It has been well established that T helper type 2...
Search relevance: 68.69 | Views last month: 0 -
Background The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the Ile105→Val105 substitution...
Search relevance: 62.59 | Views last month: 0 -
The prevalence of a sedentary (SED) life style combined with calorically rich diets has spurred the rise in childhood obesity which, in turn, translates to adverse health effects in adulthood....
Search relevance: 43.33 | Views last month: 1
