Found 37 datasets matching "genetic-polymorphisms".
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The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to...
Search relevance: 205.70 | Views last month: 0 -
Background Current efforts to study the genetic underpinnings of higher brain functions have been lacking appropriate phenotypes to describe cognition. One of the problems is that many...
Search relevance: 122.18 | Views last month: 0 -
Background Circulating levels of tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) have been associated with outcome in solid and hematologic malignancies. Within the TNF gene and the...
Search relevance: 121.29 | Views last month: 0 -
This data set contains a description of 3 mitochondrial DNA and 93 nuclear DNA Single Nucleotide Polymorphism (SNP) loci and sequence information developed through double digest restriction-site...
Search relevance: 77.65 | Views last month: 0 -
Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major achievements have occurred in...
Search relevance: 75.33 | Views last month: 3 -
In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of granuloma formation and since...
Search relevance: 73.02 | Views last month: 0 -
Asthma is the most common chronic childhood disease in the developed nations, and is a complex disease that has high social and economic costs. Studies of the genetic etiology of asthma offer a...
Search relevance: 72.95 | Views last month: 0 -
Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) are common, frequently related conditions in people generally over 50 years of age. Most studies have shown an...
Search relevance: 70.27 | Views last month: 0 -
The fathead minnow (Pimephales promelas) is a key model of vertebrate toxicity. Standardized tests of toxicity in fathead minnow have been developed to support regulatory science, and much is...
Search relevance: 69.34 | Views last month: 0 -
Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2) cytokine gene cluster on...
Search relevance: 65.49 | Views last month: 1 -
Hoary bats are among the bat species most commonly killed by turbine strikes in the midwestern United States. The impact of this mortality on species census size is not understood, due in part to...
Search relevance: 61.47 | Views last month: 0 -
These data were compiled to support effective conservation for species within Astragalus sect. Humillimi. Two species, A. cremnophylax var. cremnophylax and A. humillimus are federally listed as...
Search relevance: 59.55 | Views last month: 0 -
Background Genetic screens in Drosophila have provided a wealth of information about a variety of cellular and developmental processes. It is now possible to screen for mutant phenotypes...
Search relevance: 58.02 | Views last month: 0 -
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to...
Search relevance: 57.38 | Views last month: 0 -
This data release comprises a dataset that contains sample collection information and microsatellite genotypes, and another dataset that contains single nucleotide polymorphism (SNP) genotypes...
Search relevance: 56.89 | Views last month: 0 -
Background Women may be at increased risk for venous thromboembolism (VTE) as compared with men. We studied the effects of genetic and biochemical markers of thrombophilia in women, in...
Search relevance: 56.14 | Views last month: 3 -
Genetic linkage maps are valuable tools in evolutionary biology; however, their availability for wild populations is extremely limited. Fundulus heteroclitus (Atlantic killifish) is a...
Search relevance: 54.79 | Views last month: 1 -
Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA,...
Search relevance: 54.12 | Views last month: 0 -
Mitochondrial DNA markers have elucidated patterns of connectivity between green turtle nesting populations (rookeries) and juveniles foraging in neritic nursery habitats. However, missing rookery...
Search relevance: 54.03 | Views last month: 0 -
Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of...
Search relevance: 52.65 | Views last month: 0
