Found 32 datasets matching "high-throughput screening assay".
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Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology...
Search relevance: 287.94 | Views last month: 0 -
Dataset for Sakamuru, S., Ma, D., Pierro, J. D., Baker, N. C., Kleinstreuer, N., Cali, J. J., Knudsen, T. B., & Xia, M. (2024). Development and validation of CYP26A1 inhibition assay for...
Search relevance: 271.21 | Views last month: 0 -
Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol...
Search relevance: 262.50 | Views last month: 0 -
Dataset for article ‘Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening’ published 02/16/2022...
Search relevance: 254.33 | Views last month: 0 -
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body, facilitating predictions between...
Search relevance: 191.37 | Views last month: 2 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 117.21 | Views last month: 0 -
In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
Search relevance: 104.71 | Views last month: 1 -
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human...
Search relevance: 102.10 | Views last month: 0 -
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput...
Search relevance: 101.31 | Views last month: 0 -
We introduce a new high-throughput transcriptomics (HTTr) platform comprised of a collagen sandwich primary rat hepatocyte culture and the TempO-Seq assay for screening and prioritizing potential...
Search relevance: 99.49 | Views last month: 5 -
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput...
Search relevance: 97.63 | Views last month: 1 -
Most of the data illustrates the effects that some e-cigarette flavoring agents, as well as some of the chemical components of those flavoring agents, directly have on the cytochrome P450 2A6...
Search relevance: 93.98 | Views last month: 0 -
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
Search relevance: 93.28 | Views last month: 0 -
The datasets provide physicochemical endpoint values (volumes, pH) for exhaled breath condensate collected with spontaneous breathing and "controlled" breathing patterns. The controlled breathing...
Search relevance: 93.24 | Views last month: 0 -
Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints. Table S2. Agreement with OECD reference AR agonists. Table S3. Agreement with OECD reference ER...
Search relevance: 93.11 | Views last month: 0 -
These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used. This dataset is associated...
Search relevance: 92.13 | Views last month: 0 -
Development of the neurovascular unit (NVU) is a complex, multistage process that requires orchestrated cell signaling mechanisms across several cell types and ultimately results in the formation...
Search relevance: 88.02 | Views last month: 1 -
This excel file contains 7 tabs, each tabs contains the data for one specific figure in the paper. Description of the data and column names is also provided in each tab. This dataset is...
Search relevance: 87.74 | Views last month: 1 -
Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake. This dataset is associated with the following...
Search relevance: 87.74 | Views last month: 1 -
The objective of this study was to develop a medium-throughput organotypic screening assay comprised of reconstructed human thyroid microtissues to quantitatively evaluate the disruptive effects...
Search relevance: 86.03 | Views last month: 1
