Found 54 datasets matching "androgen".
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Data and supplemental files from COMPARA (A large-scale modeling project). COMPARA combined multiple models developed in collaboration with modelers and computational toxicology scientists from 25...
Search relevance: 130.10 | Views last month: 0 -
Repository for supplemental files and code for paper titled "High-throughput AR Dimerization Assay Identifies Androgen Disrupting Chemicals and Metabolites", 2022. This dataset is associated...
Search relevance: 129.06 | Views last month: 0 -
A diverse data set of 1667 chemicals with AR experimental activity were provided by the U.S. EPA from the oxicity Forecaster (ToxCast) program which generates data using in vitro high-throughput...
Search relevance: 124.55 | Views last month: 0 -
DNA microarrays were used to examine the temporal program of gene expression following treatment of a human prostate cancer cell line with androgen. Significant changes in levels of transcripts of...
Search relevance: 123.95 | Views last month: 0 -
Background The cyclin-dependent kinase inhibitor p27 is a putative tumor suppressor that is downregulated in the majority of human prostate cancers. The mechanism of p27 down-regulation...
Search relevance: 122.82 | Views last month: 0 -
Figures, tables, data for "Sara M F Vliet, Kristan J Markey, Scott G Lynn, Anna Adetona, Dawn Fallacara, Patricia Ceger, Neepa Choksi, Agnes L Karmaus, AtLee Watson, Andrew Ewans, Amber B Daniel,...
Search relevance: 120.22 | Views last month: 1 -
Screening certain environmental chemicals for their ability to interact with endocrine targets, including the androgen receptor (AR), is an important global concern. We previously developed a...
Search relevance: 118.33 | Views last month: 0 -
Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol...
Search relevance: 117.64 | Views last month: 0 -
This data set provides means and variance for all figures included in the manuscript. This dataset is associated with the following publication: Murr, A., A. Buckalew, G. DeVane, J. Bailey, J....
Search relevance: 116.93 | Views last month: 0 -
Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity. This...
Search relevance: 114.69 | Views last month: 0 -
Datasets used in ORD-023417: Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. This dataset is associated with the following...
Search relevance: 112.94 | Views last month: 0 -
Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a simple AOP network...
Search relevance: 111.64 | Views last month: 0 -
Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house...
Search relevance: 106.19 | Views last month: 0 -
Background Modulation of the expression of retinoic acid receptors (RAR) α and γ in adult rat prostate by testosterone (T) suggests that RAR signaling events might mediate some of the...
Search relevance: 103.78 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays...
Search relevance: 102.04 | Views last month: 0 -
The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR) antagonist, flutamide....
Search relevance: 96.15 | Views last month: 0 -
Metabolite Input Files for Determining Biochemical Pathways Impacted by Spironolactone Exposures of Fathead Minnows (Pimephales promelas) Using the Mummichog Software package. This dataset is...
Search relevance: 91.24 | Views last month: 0 -
"Morshead ML, Jensen KM, Ankley GT, Vliet S, LaLone CA, Aller AV, Watanabe KH, Villeneuve DL. Putative adverse outcome pathway development based on physiological responses of female fathead...
Search relevance: 84.31 | Views last month: 0 -
The paper has data generated by NIH and the EPA coauthors provided input into the preparation of the manuscript. This dataset is not publicly accessible because: Data was not collected in EPA labs...
Search relevance: 80.06 | Views last month: 0 -
Triclocarban (TCC) is a widely used antimicrobial agent that is routinely detected in surface waters. The present study was designed to examine TCC’s efficacy and mode of action as a reproductive...
Search relevance: 76.16 | Views last month: 1
