Found 26 datasets matching "enzyme-inhibition".
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This data set contains three spreadsheets with results of Influenza A Virus (IAV) screening in blood from Pacific, Red-throated, and Yellow-billed Loons at three locations in Alaska. Loons were...
Search relevance: 89.17 | Views last month: 0 -
These data (in two spreadsheets) are the results of screening for influenza A viruses (IAV) in blood from wild animals that utilize the Arctic region of Alaska. 758 blood samples from nine...
Search relevance: 83.51 | Views last month: 0 -
Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast chemicals against this enzyme. This...
Search relevance: 80.12 | Views last month: 0 -
Supplementary materials for "Olker JH, Korte JJ, Haselman JT, Hornung MW, Degitz SJ. Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase. Aquat Toxicol....
Search relevance: 73.01 | Views last month: 0 -
Background This work represents an extensive MD simulation / water-dynamics studies on a series of complexes of inhibitors (leupeptin, E-64, E-64-C, ZPACK) and plant cysteine proteases...
Search relevance: 72.36 | Views last month: 0 -
The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the ToxCast Phase 1_v2, Phase 2, and...
Search relevance: 71.93 | Views last month: 0 -
The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase inhibition on anterior swim...
Search relevance: 66.92 | Views last month: 1 -
The results of recent randomized trials to test the influence of antioxidants on coronary-event rates and prognosis in patients with coronary-artery disease were disappointing. In none of these...
Search relevance: 66.27 | Views last month: 0 -
Background Most test systems for acetylcholinesterase activity (E.C.3.1.1.7.) are using toxic inhibitors (BW284c51 and iso-OMPA) to distinguish the enzyme from butyrylcholinesterase...
Search relevance: 65.70 | Views last month: 0 -
These data describe the results of virus isolation from oropharyngeal/cloacal swabs and testing of sera by a commercial blocking enzyme-linked immunosorbent assay (bELISA) and hemagglutinin (HA)...
Search relevance: 65.50 | Views last month: 0 -
Long-term treatment with angiotensin-converting enzyme inhibitors reduces post-infarction morbidity and mortality in patients with left ventricular (LV) systolic dysfunction or symptomatic heart...
Search relevance: 65.45 | Views last month: 0 -
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
Search relevance: 56.17 | Views last month: 2 -
Background The signal transduction pathways mediated by retinoic acid play a critical role in the regulation of cell growth and differentiation during embryogenesis and hematopoiesis as...
Search relevance: 55.30 | Views last month: 0 -
Background The tryptophan catabolizing enzyme, indoleamine 2,3, dioxygenase (IDO) is one of two mammalian enzymes, which can catabolize the rarest essential amino acid, tryptophan. IDO...
Search relevance: 55.24 | Views last month: 0 -
Predictive models and frameworks for linking inhibition of the enzyme aromatase, as measured in non-animal high throughput screening assays, to adverse effects on reproduction in fish have been...
Search relevance: 54.59 | Views last month: 0 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 53.81 | Views last month: 0 -
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
Search relevance: 51.99 | Views last month: 1 -
Background During apoptosis, Ca2+-dependent events participate in the regulation of intracellular and morphological changes including phosphatidylserine exposure in the exoplasmic...
Search relevance: 50.43 | Views last month: 0 -
Background Cellulose acetate phthalate (CAP), a promising candidate microbicide for prevention of sexual transmission of the human immunodeficiency virus type 1 (HIV-1) and other...
Search relevance: 45.46 | Views last month: 1 -
Background The human FHIT gene is inactivated early in the development of many human cancers and loss of Fhit in mouse predisposes to cancer while reintroduction of FHIT suppresses tumor...
Search relevance: 45.08 | Views last month: 0
